- Are Aldara, Zyclara and Efudex the Same Thing?
- What Are Possible Side Effects of Efudex?
- What Are Possible Side Effects of Aldara, Zyclara?
- What is Efudex?
- What is Aldara, Zyclara?
- What Drugs Interact with Efudex?
- What Drugs Interact with Aldara, Zyclara?
- How Should Efudex Be Taken?
- How Should Aldara, Zyclara Be Taken?
Are Efudex and Aldara, Zyclara the Same Thing?
Efudex (fluorouracil) topical and Aldara, Zyclara (imiquimod) topical (for the skin) are used to treat scaly overgrowths of skin (actinic or solar keratoses). Efudex and Aldara, Zyclara may also be used in the treatment of superficial basal cell carcinoma.
Side effects of Efudex and Aldara, Zyclara that are similar include treatment area reactions (such as skin redness, swelling, irritation, burning, dryness, pain, tenderness, itching, thickening/hardening of the skin, peeling/flaking/scabbing/crusting, or leaking a clear fluid), or changes in skin color at the site of application.
Side effects of Efudex that are different from Aldara, Zyclara include rash, eye irritation (e.g., stinging, watering), trouble sleeping, irritability, temporary hair loss, or abnormal taste in the mouth.
Side effects of Aldara, Zyclara that are different from Efudex include dizziness, chest pain, back pain, cold sores, fever blisters, cold symptoms (such as stuffy nose, sneezing, sore throat), flu-like symptoms (such as fever, tiredness, muscle aches), nausea, diarrhea, loss of appetite, or vaginal itching or discharge.
What Are Possible Side Effects of Efudex?
Common side effects of Efudex include:
- skin irritation,
- peeling (exfoliation),
- changes in skin color at the site of application, or other local reactions.
- Other side effects of Efudex include eye irritation (e.g., stinging, watering),
- trouble sleeping,
- temporary hair loss, or
- abnormal taste in the mouth.
Tell your doctor if you have rare but very serious side effects of Efudex including:
- stomach or abdominal pain,
- bloody diarrhea,
- signs of infection (e.g., fever, chills, persistent sore throat),
- easy bruising or bleeding, or
- mouth sores.
What Are Possible Side Effects of Aldara, Zyclara?
Common side effects of Aldara, Zyclara include:
- treatment area reactions such as skin redness, swelling, itching, irritation, dryness, burning, pain, tenderness, thickening/hardening of the skin, peeling/flaking/scabbing/crusting, or leaking a clear fluid.
- Changes in skin color of the treated area may occur and may not go away.
- Other side effects of Aldara, Zyclara topical include headache,
- chest pain,
- back pain,
- cold sores,
- fever blisters,
- cold symptoms (such as stuffy nose, sneezing, sore throat),
- flu-like symptoms (such as fever, tiredness, muscle aches),
- loss of appetite, or
- vaginal itching or discharge.
What Is Efudex?
Efudex (fluorouracil) topical contains an antineoplastic antimetabolite used to treat scaly overgrowths of skin (actinic or solar keratoses). Efudex may also be used in the treatment of superficial basal cell carcinoma. It works by causing the death of cells that are growing fastest, such as abnormal skin cells. Efudex is available in generic form.
What Is Aldara, Zyclara?
Aldara, Zyclara (imiquimod) topical (for the skin) is an immune response modifier used to treat actinic keratosis (a condition caused by too much sun exposure) on the face and scalp. Aldara, Zyclara is also used to treat a minor form of skin cancer called superficial basal cell carcinoma, when surgery would not be an appropriate treatment. Aldara, Zyclara also treats genital warts that appear on the outside of the body, but is not a cure for genital warts. Aldara, Zyclara topical is available in generic form.
What Drugs Interact With Efudex?
Do not use other prescription or over-the-counter skin products without first talking to your doctor during treatment with Efudex topical. They may interfere with treatment or increase irritation to the skin. Other drugs may also interact with Efudex topical. Talk to your doctor before taking any prescription or over-the-counter medicines. Efudex topical must not be used during pregnancy. It may harm a fetus. It is not known if this medication passes into breast milk. Due to the potential risk to a nursing infant, breastfeeding is not recommended while using this drug.
What Drugs Interact With Aldara, Zyclara?
It is not likely that other drugs you take orally or inject will have an effect on topically applied Aldara, Zyclara. But many drugs can interact with each other. Tell your doctor all prescription and over-the-counter medications and supplements you use. During pregnancy, Aldara, Zyclara should be used only when prescribed. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.
How Should Efudex Be Taken?
The dose of Efudex topical is to apply a small amount of the cream to the area that is to be treated, once or twice daily after cleansing. Treatment lasts 2-6 weeks depending on the condition being treated. Wash hands immediately afterward.
How Should Aldara, Zyclara Be Taken?
Aldara, Zyclara Cream should be applied 2 times per week for a full 16 weeks to a defined treatment area on the face or scalp (but not both concurrently). Before applying the cream, the patient should wash hands and the treatment area with mild soap and water and allow the area to dry thoroughly. Avoid contact with eyes, lips and nostrils.
Skin Problems and Treatments Resources
All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA).
Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.
Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.
The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.
As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current.
Any missing drug warnings or information does not in any way guarantee the safety, effectiveness, or the lack of adverse effects of any drug. The drug information provided is intended for reference only and should not be used as a substitute for medical advice.
If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information.
You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.
FDA. Efudex Prescribing Information.
FDA. Aldara Prescribing Information.