Emgality vs. Maxalt

Reviewed on 9/17/2019

Are Emgality and Maxalt the Same Thing?

Emgality (galcanezumab-gnlm) and Maxalt (rizatriptan) are indicated for the treatment of migraine in adults.

Emgality and Maxalt belong to different drug classes. Emgality is a calcitonin-gene related peptide antagonist and Maxalt is a selective serotonin receptor agonist (a "triptan").

Side effects of Emgality that are different from Maxalt include injection site reactions (such as pain, redness, and itching).

Side effects of Maxalt that are different from Emgality include mild headache (not a migraine), dry mouth, nausea, feeling of pain or tightness in the jaw, neck, or throat; pressure or heavy feeling in any part of your body, dizziness, drowsiness, tired feeling, weakness, feelings of tingling/numbness/prickling/heat, and flushing (warmth, redness, or tingling feeling under your skin).

Emgality may interact with other drugs.

Maxalt may interact with other migraine headache medicines, medicines to treat depression or a psychiatric disorder, narcotics, and medicines to prevent nausea and vomiting.

What Are Possible Side Effects of Emgality?

Common side effects of Emgality include:

  • injection site reactions such as pain, redness, and itching

What Are Possible Side Effects of Maxalt?

Common side effects of Maxalt include:

  • mild headache (not a migraine),
  • dry mouth,
  • nausea;
  • feeling of pain or tightness in the jaw, neck, or throat;
  • pressure or heavy feeling in any part of your body,
  • dizziness,
  • drowsiness,
  • tired feeling,
  • weakness,
  • feelings of tingling/numbness/prickling/heat, or
  • flushing (warmth, redness, or tingling feeling under your skin).

What Is Emgality?

Emgality (galcanezumab-gnlm) is a calcitonin-gene related peptide antagonist indicated for the preventive treatment of migraine in adults.

What Is Maxalt?

Maxalt (rizatriptan) tablets is a selective 5-hydroxytryptamine1B/1D (5-HT1B/1D) receptor agonist used to treat the pain of migraine headache. Maxalt is believed to work by narrowing the blood vessels around the brain and by decreasing levels of substances involved in the development of migraine pain. Maxalt will only treat a headache that has already begun. Maxalt will not prevent headaches or reduce the number of attacks.

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What Drugs Interact With Emgality?

Emgality may interact with other drugs. Tell your doctor all medications and supplements you use.

What Drugs Interact With Maxalt?

Maxalt may interact with other migraine headache medicines, propranolol, or antidepressants. Tell your doctor all medications and supplements you use. It is not known whether this medication is harmful to an unborn baby. Before taking rizatriptan, tell your doctor if you are pregnant or plan to become pregnant during treatment. It is also not known whether rizatriptan passes into breast milk or if it could harm a nursing baby. Consult your doctor before breastfeeding.

How Should Emgality Be Taken?

The recommended dosage of Emgality is a 240 mg loading dose (administered as two consecutive injections of 120 mg each), followed by monthly doses of 120 mg.

How Should Maxalt Be Taken?

The adult dose of Treximet is 1 mg or 2.5 mg tablets taken with fluid. The dose may be repeated once after 4 hours, for a maximum dose of 5 mg in a 24-hour period.

QUESTION

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References
Lilly. Emgality Drug Information.

www.emgality.com/?

Merck. Maxalt Product Information.

https://www.merck.com/product/usa/pi_circulars/m/maxalt/maxalt_pi.pdf

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