Enskyce

What Is Enskyce?

Enskyce (desogestrel and ethinyl estradiol tablets) are oral contraceptives indicated for the prevention of pregnancy in women who elect to use this product as a method of contraception. Enskyce is available in generic form.

What Are Side Effects of Enskyce?

Common side effects of Enskyce include:

• nausea,
• vomiting,
• abdominal cramps,
• bloating,
• breakthrough bleeding,
• spotting,
• changes in menstrual flow,
• missed periods,
• swelling,
• freckles or darkening of facial skin,
• breast tenderness or enlargement,
• nipple discharge,
• weight gain or loss,
• changes in vaginal discharge,
• migraine, rash (allergic),
• depression,
• vaginal yeast infection,
• and intolerance to contact lenses.

Cigarette smoking increases the risk of serious cardiovascular side effects from use of oral contraceptives such as Enskyce. Women who use oral contraceptives including Enskyce are strongly advised not to smoke.

Dosage for Enskyce

The dosage of Enskyce for the initial cycle of therapy is one light orange "active" tablet administered daily from the 1 day through the 21 day of the menstrual cycle, counting the first day of menstrual flow as "Day 1". Tablets are taken without interruption as follows: One light orange "active" tablet daily for 21 days, then one green "reminder" tablet daily for 7 days. After 28 tablets have been taken, a new course is started and a light orange "active" tablet is taken the next day.

What Drugs, Substances, or Supplements Interact with Enskyce?

Enskyce may interact with:

• phenytoin,
• barbiturates,
• carbamazepine,
• bosentan,
• felbamate,
• griseofulvin,
• oxcarbazepine,
• rifampicin,
• topiramate,
• rifabutin,
• rufinamide,
• aprepitant,
• St. John's wort,
• azole antifungals,
• grapefruit juice,
• HIV/Hepatitis C virus (HCV) protease inhibitors,
• non-nucleoside reverse transcriptase inhibitors,
• colesevelam,
• cyclosporine,
• prednisolone,
• theophylline,
• tizanidine,
• voriconazole,
• acetaminophen,
• clofibric acid,
• morphine,
• salicylic acid,
• temazepam,
• lamotrigine,
• and thyroid hormone replacement therapy.

Tell your doctor all medications and supplements you use.

Enskyce During Pregnancy and Breastfeeding

Enskyce is not recommended for use during pregnancy. Small amounts of Enskyce pass into breast milk and may cause adverse reactions in nursing infants. Breastfeeding while using Enskyce is not recommended.

Additional Information

Our Enskyce (desogestrel and ethinyl estradiol tablets) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

© Enskyce Patient Information is supplied by Cerner Multum, Inc. and Enskyce Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.