Entex Pse Side Effects Center

Last updated on RxList: 7/7/2022
Entex Pse Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

What Is Entex Pse?

Entex PSE (pseudoephedrine and guaifenesin) is a combination decongestant and expectorant used to treat stuffy nose, sinus congestion, and cough caused by allergies or the common cold. Entex PSE is available in generic form.

What Are Side Effects of Entex Pse?

Common side effects of Entex PSE include:

  • dizziness
  • headache
  • restlessness
  • excited feeling
  • sleep problems (insomnia)
  • nausea
  • vomiting
  • stomach upset
  • loss of appetite
  • flushing (warmth, redness, or tingly feeling under your skin)
  • skin rash, or
  • itching

Seek medical care or call 911 at once if you have the following serious side effects:

  • Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
  • Serious heart symptoms such as fast, irregular, or pounding heartbeats; fluttering in your chest; shortness of breath; and sudden dizziness, lightheartedness, or passing out;
  • Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors.

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

Dosage for Entex Pse

The recommended dose of Entex PSE for adults and adolescents 12 years of age and older is one tablet twice daily (every 12 hours). The dose for children 6 to under 12 years is one-half (1/2) tablet twice daily (every 12 hours).

What Drugs, Substances, or Supplements Interact with Entex Pse?

Entex PSE may interact with methyldopa, blood pressure medications, beta-blockers, or antidepressants. Tell your doctor all medications and supplements you use.

Entex Pse During Pregnancy or Breastfeeding

During pregnancy, It is unknown if Entex PSE will harm a fetus. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. This drug may pass into breast milk and may harm a nursing baby. Consult your doctor before breastfeeding.

Additional Information

Our Entex PSE (pseudoephedrine and guaifenesin) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Which illness is known as a viral upper respiratory tract infection? See Answer
Entex Pse Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using guaifenesin and pseudoephedrine and call your doctor at once if you have:

  • fast, pounding, or uneven heartbeat; or
  • severe anxiety or nervousness.

Common side effects may include:

  • dry mouth, nose, or throat;
  • upset stomach, loss of appetite, vomiting;
  • feeling excited or restless (especially in children);
  • sleep problems (insomnia); or
  • headache, dizziness.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


A Cold or The Flu? How to Tell the Difference See Slideshow
Entex Pse Professional Information


Gastrointestinal:   nausea and vomiting.

Central Nervous System:   nervousness, dizziness, sleeplessness, lightheadedness, tremor, hallucinations, convulsions, CNS depression, fear, anxiety, headache, increased irritability or excitement.

Cardiovascular:   palpitations, tachycardia, cardiovascular collapse and death.

General:   weakness.

Respiratory:   respiratory difficulties.

Read the entire FDA prescribing information for Entex Pse (Pseudoephedrine and Guaifenesin)

© Entex Pse Patient Information is supplied by Cerner Multum, Inc. and Entex Pse Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

Health Solutions From Our Sponsors