Are Entresto and Ranexa the Same Thing?
Ranexa is prescribed to treat chronic angina.
Side effects of Ranexa that are different from Entresto include spinning sensation, nausea, vomiting, stomach pain, constipation, headache, dry mouth, weakness, ringing in your ears, swelling in hands/ankles/feet, slow/fast/irregular heartbeats, tremors, blood in the urine, and shortness of breath.
Entresto may interact with angiotensin-converting-enzyme (ACE) inhibitors, other angiotensin receptor blockers (ARBs), potassium-sparing diuretics, nonsteroidal anti-inflammatory drugs (NSAIDs), or lithium.
Ranexa may interact with grapefruit and grapefruit juice, antibiotics, antifungals, other medicines to treat heart disease, cholesterol-lowering medicines, diabetes medications, medicines to prevent organ transplant rejection, medicines to treat mental illness, or medicines to treat or prevent nausea and vomiting caused by chemotherapy or radiation.
What Are Possible Side Effects of Entresto?
Side effects of Entresto include:
- low blood pressure (hypotension),
- high blood potassium (hyperkalemia),
- dizziness, and
- kidney (renal) failure
What Are Possible Side Effects of Ranexa?
Common side effects of Ranexa include:
- stomach upset,
- flushing (warmth, redness, or tingly feeling),
- memory problems,
- loss of balance or coordination,
- blurred vision,
- double vision,
- eye redness,
- spinning sensation,
- sleep problems (insomnia),
- stuffy nose,
- itching, or
- rash, especially during the first few days as your body adjusts to this medication.
Tell your doctor if you experience serious side effects of Ranexa including:
- flu symptoms,
- slow heart rate,
- feeling like you might pass out,
- seizures (convulsions), or
- jaundice (yellowing of your skin or eyes).
What Is Entresto?
Entresto (sacubitril and valsartan) is a combination of a neprilysin inhibitor and an angiotensin II receptor blocker indicated to reduce the risk of cardiovascular death and hospitalization for heart failure in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction.
What Is Ranexa?
What Drugs Interact With Entresto?
Entresto may interact with angiotensin-converting-enzyme (ACE) inhibitors, other angiotensin receptor blockers (ARBs), potassium-sparing diuretics, nonsteroidal anti-inflammatory drugs (NSAIDs), or lithium. Tell your doctor all medications and supplements you use. Entresto is not recommended for use during pregnancy. It may harm a fetus. Entresto is not recommended for use while breastfeeding.
What Drugs Interact With Ranexa?
Ranexa may interact with other medicines that can make you sleepy or slow your breathing (such as cold or allergy medicines, narcotic pain medicines, sleeping pills, muscle relaxers, and medicines for depression, seizure, anxiety), and heart or blood pressure medications. Ranexa may also interact with carbamazepine, diazepam, fluoxetine, olanzapine, fluvoxamine, omeprazole, rifampin, or medications to treat Parkinson's disease.
How Should Entresto Be Taken?
Entresto (ziprasidone HCl) is available as capsules and Entresto (ziprasidone mesylate) is available as an injection for intramuscular use.
Entresto Capsules should be administered at an initial daily dose of 20 mg twice daily with food. For intramuscular dosing, the recommended dose of Entresto is 10 mg to 20 mg administered as required up to a maximum dose of 40 mg per day.
How Should Ranexa Be Taken?
The recommended starting dose of Entresto is 49/51 mg twice-daily. Double the dose of Entresto after 2 to 4 weeks to the target maintenance dose of 97/103 mg twice-daily, as tolerated by the patient.
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Novartis. Entresto Product Information.
Gilead Sciences, Inc. Ranexa Prescribing Information.