Medical Editor: John P. Cunha, DO, FACOEP Last updated on RxList: 9/29/2021
Ertaczo Side Effects Center

What Is Ertaczo?

Ertaczo (sertaconazole nitrate) Cream is an antifungal medication used to treat fungal infections of the skin such as athlete's foot. Serious side effects are not expected to occur with the use of Ertaczo Cream topical.

What Are Side Effects of Ertaczo?

Side effects of Ertaczo Cream include:

  • burning,
  • swelling,
  • irritation,
  • tenderness,
  • discoloration, or
  • dry skin

Dosage for Ertaczo

The recommended dose to treat interdigital tinea pedis is to apply Ertazco cream twice daily for 4 weeks. Sufficient cream should be applied to cover both the affected areas between the toes and the immediately surrounding healthy skin.

What Drugs, Substances, or Supplements Interact with Ertaczo?

Do not use other topical products on the treated area, unless otherwise directed by your doctor. Other topical products may affect the absorption or effectiveness of Ertaczo topical. Although unlikely, other medications may interact with Ertazco topical. Tell your doctor all medications and supplements you use.

Ertaczo During Pregnancy and Breastfeeding

Ertaczo should be used only when prescribed during pregnancy. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

Additional Information

Our Ertaczo (sertaconazole nitrate) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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Ertaczo Consumer Information

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Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • severe burning, redness, or stinging after applying the medicine;
  • itching or blistering skin; or
  • swelling or oozing from the skin.

Common side effects may include:

  • dryness of treated skin;
  • skin tenderness; or
  • mild rash or skin irritation where the medicine was applied.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Ertaczo (Sertaconazole Nitrate)


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Ertaczo Professional Information


Clinical Trials Experience

Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.

In clinical trials, cutaneous adverse events occurred in 7 of 297 (2%) subjects (2 of them severe) receiving ERTACZO cream, 2%, and in 7 of 291 (2%) subjects (2 of them severe) receiving vehicle. These reported cutaneous adverse events included contact dermatitis, dry skin, burning skin, and application site skin tenderness.

In a dermal sensitization trial, 8 of 202 evaluable subjects tested with ERTACZO cream, 2%, and 4 of 202 evaluable subjects tested with vehicle exhibited a erythematous reaction in the challenge phase. There was no evidence of cumulative irritation or contact sensitization in a repeated insult patch test involving 202 healthy volunteers.

Postmarketing Experience

The following adverse reactions have been identified during post-approval use of ERTACZO cream, 2%. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

Cutaneous adverse events: erythema, pruritus, vesiculation, desquamation, and hyperpigmentation.

Read the entire FDA prescribing information for Ertaczo (Sertaconazole Nitrate)

© Ertaczo Patient Information is supplied by Cerner Multum, Inc. and Ertaczo Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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