Definition of Estrogen-associated blood clots

Reviewed on 3/29/2021

Estrogen-associated blood clots: Blood clots are occasional but serious side effects of estrogen therapy. They are dose-related, that is, they occur more frequently with higher doses of estrogen.

Estrogen therapy preparations (all of which carry this risk) include:

The brand names of the estrogen therapy preparations carrying this risk include:

  • CLIMARA (estradiol)
  • ESTRACE (estradiol)
  • ESTRADERM (estradiol)
  • ESTRATAB (esterified estrogens)
  • ESTRATEST (esterified estrogens and methyltestosterone \)
  • MENEST (esterified estrogens)
  • OGEN (estropipate)
  • PREMARIN (estrogens conjugated)
  • PREMPHASE (estrogens conjugated and medroxyprogesterone)
  • PREMPRO (estrogens conjugated and medroxyprogesterone)

Cigarette smokers on estrogen therapy are at a higher risk than non-smokers for blood clots. Therefore, patients requiring estrogen therapy are strongly encouraged to quit smoking.

SLIDESHOW

Pelvic Pain: What's Causing Your Pelvic Pain? See Slideshow

Health Solutions From Our Sponsors