Are Eticovo and Hadlima the Same Thing?
Eticovo (etanercept-ykro) and Hadlima (adalimumab-bwwd) are tumor necrosis factor (TNF) blockers used to treat rheumatoid arthritis (RA), juvenile idiopathic arthritis (JIA), psoriatic arthritis (PsA), ankylosing spondylitis (AS), and plaque psoriasis (Ps).
Hadlima is also used to treat adult Crohn's disease (CD) and ulcerative colitis (UC).
Hadlima is biosimilar to Humira (adalimumab) and Eticovo is biosimilar to Enbrel (etanercept).
Side effects of Eticovo that are different from Hadlima include diarrhea, itching, fever, and hives.
Side effects of Hadlima and Eticovo that are similar include infections (such as upper respiratory infections, nasopharyngitis, sinusitis, and influenza), injection site reactions (redness, itching, bleeding, pain, and swelling), and rash.
Side effects of Hadlima that are different from Eticovo include headache.
Both Hadlima and Eticovo may interact with abatacept, anakinra, and live vaccines.
Eticovo may also interact with cyclophosphamide and sulfasalazine.
Hadlima may also interact with warfarin, cyclosporine, and theophylline.
What Are Possible Side Effects of Eticovo?
Side effects of Eticovo include:
- infections (such as upper respiratory infections, nasopharyngitis, sinusitis, and influenza),
- injection site reactions,
- diarrhea,
- rash,
- itching,
- fever, and
- hives
What Are Possible Side Effects of Hadlima?
Common side effects of Hadlima include:
- infections (e.g. upper respiratory tract, sinusitis),
- injection site reactions (redness, itching, bleeding, pain, and swelling),
- headache, and
- rash
What Is Eticovo?
Eticovo (etanercept-ykro) is a tumor necrosis factor (TNF) blocker indicated for the treatment of rheumatoid arthritis (RA), polyarticular juvenile idiopathic arthritis (JIA) in patients aged 2 years or older, psoriatic arthritis (PsA), ankylosing spondylitis (AS), and plaque psoriasis (PsO) in patients 4 years or older. Eticovo is biosimilar to Enbrel (etanercept).
What Is Hadlima?
Hadlima (adalimumab-bwwd) is a tumor necrosis factor (TNF) blocker indicated for treatment of rheumatoid Arthritis (RA), juvenile idiopathic arthritis (JIA), psoriatic arthritis (PsA), ankylosing spondylitis (AS), adult Crohn's disease (CD), ulcerative colitis (UC), and plaque psoriasis (Ps). Hadlima is biosimilar to Humira (adalimumab).
What Drugs Interact With Eticovo?
Eticovo may interact with "live vaccines," anakinra, abatacept, and cyclophosphamide, and sulfasalazine. Tell your doctor all medications and supplements you use and all vaccines you recently received. Tell your doctor if you are pregnant or plan to become pregnant before using Eticovo; it is unknown how it would affect a fetus. Eticovo passes into breast milk in low levels. Consult your doctor before breastfeeding.
What Drugs Interact With Hadlima?
Hadlima may interact with abatacept, anakinra, warfarin, cyclosporine, theophylline, and live vaccines.
How Should Eticovo Be Taken?
Eticovo is given by injection under the skin, in the stomach or thigh area, as directed by your doctor. Follow your doctor's directions and the schedule for your doses very carefully.
How Should Hadlima Be Taken?
The dose of Eticovo to treat adult rheumatoid arthritis and psoriatic arthritis is 50 mg once weekly with or without methotrexate (MTX). The dose of Eticovo to treat ankylosing spondylitis is 50 mg once weekly. The dose of Eticovo to treat adult plaque psoriasis is 50 mg twice weekly for 3 months, followed by 50 mg once weekly. The dose of Eticovo to treat pediatric plaque psoriasis or plaque psoriasis (patients who weigh 63 kg or more) is 50 mg once weekly.
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Samsung Bioepis. Eticovo Product Information.
https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/761066s000lbl.pdf
FDA. Hadlima Product Information.
https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/761059s000lbl.pdf