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Eucrisa vs. Otezla

Are Eucrisa and Otezla the Same Thing?

Eucrisa (crisaborole) and Otezla (apremilast) are both phosphodiesterase 4 inhibitors.

Eucrisa is a topical ointment used to treat mild to moderate atopic dermatitis (eczema) in patients 2 years of age and older.

What Are Possible Side Effects of Eucrisa?

Common side effects of Eucrisa include:

  • application site pain

What Are Possible Side Effects of Otezla?

Common side effects of Otezla include:

  • diarrhea,
  • headache,
  • nausea,
  • upper respiratory tract infection,
  • vomiting,
  • runny or stuffy nose,
  • abdominal pain,
  • fatigue,
  • indigestion/heartburn,
  • decreased appetite,
  • insomnia,
  • back pain,
  • frequent bowel movements,
  • depression,
  • bronchitis,
  • tooth abscess, and
  • sinus headache.

What is Eucrisa?

Eucrisa (crisaborole) ointment, 2%, for topical use is a phosphodiesterase 4 inhibitor indicated for topical treatment of mild to moderate atopic dermatitis in patients 2 years of age and older.

What is Otezla?

Otezla (apremilast) is a phosphodiesterase 4 (PDE4) inhibitor used to treat adult patients with active psoriatic arthritis.

What Drugs Interact With Eucrisa?

Eucrisa may interact with ther drugs..

What Drugs Interact With Otezla?

Otezla may interact with CYP450 inducers (such as rifampin).

How Should Eucrisa Be Taken?

The recommended maintenance dosage is 30 mg twice daily taken orally starting on Day 6, after 5 days of an initial schedule of titration dosing.

How Should Otezla Be Taken?

The recommended maintenance dosage is 30 mg twice daily taken orally starting on Day 6, after 5 days of an initial schedule of titration dosing.

Reviewed on 8/7/2018

SOURCE:

Pfizer. Eucrisa Product Information.

https://www.eucrisa.com

Celgene Corporation. Otezla Product Information.

https://www.otezla.com

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