Eucrisa vs. Temovate

Are Eucrisa and Temovate the Same Thing?

Eucrisa (crisaborole) and Temovate (clobetasol propionate) are indicated for topical treatment of atopic dermatitis (eczema).

Temovate is also used to treat the inflammation and itching caused by a number of skin conditions such as allergic reactions and psoriasis.

Eucrisa and Temovate belong to different drug classes. Eucrisa is a phosphodiesterase 4 inhibitor and Temovate is a steroid.

What Are Possible Side Effects of Eucrisa?

Common side effects of Eucrisa include:

  • application site pain

What Are Possible Side Effects of Temovate?

Common side effects of Temovate include:

  • burning,
  • stinging,
  • itching,
  • dryness,
  • redness, or
  • rash at the application site when first applied to the skin. This should disappear in a few days as your body adjusts to Temovate.

Other side effects of Temovate include:

  • dry or cracking skin,
  • thinning or softening of your skin,
  • skin rash or irritation around your mouth,
  • swollen hair follicles,
  • temporary hair loss,
  • spider veins,
  • changes in color of treated skin,
  • blisters,
  • pimples,
  • acne,
  • crusting of treated skin,
  • extreme/unwanted hair growth,
  • "hair bumps" (folliculitis), or
  • stretch marks.

What is Eucrisa?

Eucrisa (crisaborole) ointment, 2%, for topical use is a phosphodiesterase 4 inhibitor indicated for topical treatment of mild to moderate atopic dermatitis in patients 2 years of age and older.

What is Temovate?

Temovate (clobetasol propionate) is a topical (for the skin) steroid used to treat the inflammation and itching caused by a number of skin conditions such as allergic reactions, eczema, and psoriasis.


Rosacea, Acne, Shingles, Covid-19 Rashes: Common Adult Skin Diseases See Slideshow

What Drugs Interact With Eucrisa?

Eucrisa may interact with ther drugs..

What Drugs Interact With Temovate?

Temovate may interact with corticosteroids taken by mouth or drugs that lower the immune system. Tell your doctor about all medications you are taking.

How Should Eucrisa Be Taken?

  • Use Eucrisa exactly as your healthcare provider tells you to use it.
  • Apply a thin layer of Eucrisa to the affected areas 2 times each day.
  • Wash your hands after applying Eucrisa, unless hands are being treated. If someone else applies Eucrisa for you, they should wash their hands after applying Eucrisa.

How Should Temovate Be Taken?

Temovate Cream or Ointment is applied topically (on the skin) to the affected areas twice daily. Treatment should be limited to 2 consecutive weeks and amounts greater than 50 g/week should not be used..


Eczema (also atopic eczema or atopic dermatitis) is a general medical term for many types of skin inflammation. See Answer

All drug information provided on is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA).

Any drug information published on regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.

Drug information found in the drug comparisons published on is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.

The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. assumes no responsibility for any healthcare administered to a person based on the information found on this site.

As drug information can and will change at any time, makes every effort to update its drug information. Due to the time-sensitive nature of drug information, makes no guarantees that the information provided is the most current.

Any missing drug warnings or information does not in any way guarantee the safety, effectiveness, or the lack of adverse effects of any drug. The drug information provided is intended for reference only and should not be used as a substitute for medical advice.

If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the or websites for more information.

You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.


Pfizer. Eucrisa Product Information.

DailyMed. Temovate Product Information.

Health Solutions From Our Sponsors