Euthyrox

Last updated on RxList: 1/12/2021
Euthyrox Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

What Is Euthyrox?

Euthyrox (levothyroxine sodium) is L-thyroxine (T 4) indicated in pediatric and adult patients as replacement in primary (thyroidal), secondary (pituitary), and tertiary (hypothalamic) congenital or acquired hypothyroidism; and as an adjunct to surgery and radioiodine therapy in the management of thyrotropin-dependent well-differentiated thyroid cancer. Euthyrox is available in generic form.

What Are Side Effects of Euthyrox?

Common side effects of Euthyrox are primarily those of hyperthyroidism due to therapeutic overdosage and include:

Dosage for Euthyrox

Administer a dose of Euthyrox once daily, on an empty stomach, one-half to one hour before breakfast. Administer Euthyrox at least 4 hours before or after drugs that are known to interfere with absorption.

What Drugs, Substances, or Supplements Interact with Euthyrox?

Euthyrox may interact with calcium carbonate, ferrous sulfate, bile acid sequestrants, ion exchange resins, proton pump inhibitors (PPIs), sucralfate, antacids, clofibrate, estrogen-containing oral contraceptives, estrogens (oral), heroin/methadone, 5-fluorouracil, mitotane, tamoxifen, androgens, steroids, asparaginase, glucocorticoids, slow-release nicotinic acid, salicylates, carbamazepine, furosemide, heparin, hydantoins, nonsteroidal anti-inflammatory drugs (NSAIDs), phenobarbital, rifampin, beta blockers, amiodarone, antidiabetic drugs or insulin, anticoagulants, digitalis glycosides, antidepressants, ketamine, sympathomimetics, and tyrosine-kinase inhibitors. Tell your doctor all medications and supplements you use.

Euthyrox During Pregnancy and Breastfeeding

Tell your doctor if you are pregnant or plan to become pregnant before using Euthyrox; Euthyrox dose requirements may increase during pregnancy. Euthyrox passes into breast milk. Consult your doctor before breastfeeding.

Additional Information

Our Euthyrox (levothyroxine sodium) Tablets, for Oral Use Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

QUESTION

Where is the thyroid gland located? See Answer
Euthyrox Consumer Information

3 pharmacies near 20147 have coupons for euthyrox (Brand Names:Euthyrox for 137MCG)

Walgreens
Walgreens
$57.49

Est. Regular Price

$45.67

with free coupon

View Coupon
CVS Pharmacy
CVS Pharmacy
$57.49

Est. Regular Price

$47.83

with free coupon

View Coupon
Wegmans Food Markets Inc
Wegmans Food Markets Inc
$57.49

Est. Regular Price

$48.16

with free coupon

View Coupon

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • fast or irregular heartbeats;
  • chest pain, pain spreading to your jaw or shoulder;
  • shortness of breath;
  • fever, hot flashes, sweating;
  • tremors, or if you feel unusually cold;
  • weakness, tiredness, sleep problems (insomnia);
  • memory problems, feeling depressed or irritable;
  • headache, leg cramps, muscle aches;
  • feeling nervous or irritable;
  • dryness of your skin or hair, hair loss;
  • irregular menstrual periods; or
  • vomiting, diarrhea, appetite changes, weight changes.

Certain side effects may be more likely in older adults.

Common side effects may include:

  • chest pain, irregular heartbeats;
  • shortness of breath;
  • headache, leg cramps, muscle pain or weakness;
  • tremors, feeling nervous or irritable, trouble sleeping;
  • increased appetite;
  • feeling hot;
  • weight loss;
  • changes in your menstrual periods;
  • diarrhea; or
  • skin rash, partial hair loss.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Euthyrox (Levothyroxine Sodium Tablets)

SLIDESHOW

Hyperthyroidism Symptoms and Treatment See Slideshow
Euthyrox Professional Information

SIDE EFFECTS

Adverse reactions associated with EUTHYROX therapy are primarily those of hyperthyroidism due to therapeutic overdosage [see WARNINGS AND PRECAUTIONS, OVERDOSAGE]. They include the following:

  • General: fatigue, increased appetite, weight loss, heat intolerance, fever, excessive sweating
  • Central Nervous System: headache, hyperactivity, nervousness, anxiety, irritability, emotional lability, insomnia
  • Musculoskeletal: tremors, muscular weakness and cramps
  • Cardiovascular: palpitations, tachycardia, arrhythmias, increased pulse and blood pressure, heart failure, angina, myocardial infarction, cardiac arrest
  • Respiratory: dyspnea
  • Gastrointestinal: diarrhea, vomiting, abdominal cramps and elevations in liver function tests
  • Dermatologic: hair loss, flushing, rash
  • Endocrine: decreased bone mineral density
  • Reproductive: menstrual irregularities, impaired fertility

Seizures have been reported rarely with levothyroxine therapy.

Adverse Reactions In Pediatric Patients

Pseudotumor cerebri and slipped capital femoral epiphysis have been reported in pediatric patients receiving levothyroxine therapy. Overtreatment may result in craniosynostosis in infants and premature closure of the epiphyses in pediatric patients with resultant compromised adult height.

Hypersensitivity Reactions

Hypersensitivity reactions to inactive ingredients have occurred in patients treated with thyroid hormone products. These include urticaria, pruritus, skin rash, flushing, angioedema, various gastrointestinal symptoms (abdominal pain, nausea, vomiting and diarrhea), fever, arthralgia, serum sickness and wheezing. Hypersensitivity to levothyroxine itself is not known to occur.

Read the entire FDA prescribing information for Euthyrox (Levothyroxine Sodium Tablets)

© Euthyrox Patient Information is supplied by Cerner Multum, Inc. and Euthyrox Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

Health Solutions From Our Sponsors