Evekeo vs. Mydayis

Evekeo (amphetamine sulfate tablets) and Mydayis (mixed salts of a single-entity amphetamine product) are central nervous system stimulants used to treat attention-deficit hyperactivity disorder (ADHD).

Evekeo is also used to treat a sleep disorder called narcolepsy, and may also be used as part of a short-term, weight reduction program to treat exogenous obesity.

Side effects of Evekeo and Mydayis that are similar include trouble sleeping (insomnia), decreased appetite, diarrhea, dry mouth, weight loss, palpitations, fast heart rate, and impotence.

Side effects of Evekeo that are different from Mydayis include headache, stomach ache, unpleasant taste in mouth, nervousness, dizziness, vomiting, itching, constipation, mood swings, elevated blood pressure, overstimulation, restlessness, euphoria, problems with coordination, tremor, uneasiness, hives, changes in sex drive, frequent or prolonged erections, and muscle wasting (rhabdomyolysis).

Side effects of Mydayis that are different from Evekeo include irritability, nausea, anxiety, feeling jittery, tooth grinding, depression, and menstrual pain or cramping.

Both Evekeo and Mydayis may interact with stomach acid medicines, antidepressants including MAOIs, and lithium.

Evekeo may also interact with anti-psychotic medicines, cold or allergy medicines that contain decongestants, blood pressure medications, narcotics, seizure medicines, and blood thinners.

Mydayis may also interact with acidifying or alkalinizing agents (GI and urinary), triptans, fentanyl, tramadol, tryptophan, buspirone, St. John's wort, quinidine, and ritonavir.

Withdrawal symptoms may occur if you suddenly stop taking Evekeo or Mydayis.

Common side effects of Evekeo include:

• headache,
• stomach ache,
• trouble sleeping (insomnia),
• decreased appetite,
• unpleasant taste in mouth,
• nervousness,
• dizziness,
• sexual problems (impotence in males),
• vomiting,
• itching,
• diarrhea,
• constipation,
• dry mouth,
• weight loss,
• mood swings,
• palpitations,
• fast heart rate,
• elevated blood pressure,
• overstimulation,
• restlessness,
• euphoria,
• problems with coordination,
• tremor,
• uneasiness,
• loss of appetite,
• hives,
• impotence,
• changes in sex drive,
• frequent or prolonged erections, and
• muscle wasting (rhabdomyolysis).

Common side effects of Mydayis include:

• insomnia,
• decreased appetite,
• decreased weight,
• irritability,
• nausea,
• dry mouth,
• increased heart rate,
• anxiety,
• feeling jittery,
• tooth grinding,
• depression,
• diarrhea,
• palpitations,
• menstrual pain or cramping, and
• erectile dysfunciton.

Central nervous system stimulants, including Mydayis, have a high potential for abuse and dependence.

Evekeo (amphetamine sulfate tablets) is a central nervous system stimulant used to treat a sleep disorder called narcolepsy, and to help increase attention and decrease impulsiveness and hyperactivity in patients with ADHD. Evekeo should be used as part of a total treatment program for ADHD that may include counseling or other therapies. Evekeo may also be used as part of a short-term, weight reduction program to treat exogenous obesity.

Mydayis (mixed salts of a single-entity amphetamine product) extended-release capsules are a central nervous system (CNS) stimulant indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in patients 13 years and older.

Evekeo may interact with stomach acid medicines, antidepressants including MAOIs, anti-psychotic medicines, lithium, cold or allergy medicines that contain decongestants, blood pressure medicines, narcotics, seizure medicines, or blood thinner medicines. Tell your doctor all medications and supplements you or your child use.

Mydayis may interact with acidifying or alkalinizing agents (GI and urinary), monoamine oxidase inhibitors (MAOIs), selective serotonin reuptake inhibitors (SSRIs), serotonin norepinephrine reuptake inhibitors (SNRIs), triptans, antidepressants, fentanyl, lithium, tramadol, tryptophan, buspirone, St. John's wort, quinidine, ritonavir, omeprazole, esomeprazole, pantoprazole, and cimetidine. Tell your doctor all medications and supplements you use.

The usual dose of Evekeo to treat narcolepsy is 5 to 60 mg per day in divided doses. The usual starting dose of Evekeo to treat ADHD in children from 3 to 5 years of age is 2.5 mg daily; in children 6 years of age or older, start with 5 mg once or twice daily. The usual dose of Evekeo to treat exogenous obesity is up to 30 mg daily, taken in divided doses of 5 to 10 mg, 30 to 60 minutes before meals.

The recommended starting dose of Mydayis for adults and children 13 to 17 years is 12.5 mg.