Evista vs. Prolia

Are Evista and Prolia the Same Thing?

Prolia (denosumab) and Evista (raloxifene hydrochloride) are used to treat bone loss (osteoporosis) in women who are at high risk for bone fracture after menopause.

Evista is also used to reduce the risk of invasive breast cancer in postmenopausal women who have osteoporosis or who are otherwise at risk of invasive breast cancer.

Prolia is a monoclonal antibody and Evista is an estrogen agonist/antagonist.

What Are Possible Side Effects of Evista?

Common side effects of Evista include:

Seek medical attention if you have unlikely but serious side effects of Evista including:

  • leg swelling or pain,
  • trouble breathing,
  • chest pain,
  • sudden vision changes,
  • severe headache,
  • weakness on one side of the body, or
  • confusion.

What Are Possible Side Effects of Prolia?

Common side effects of Prolia include:

You may also be more likely to get a serious infection, such as a skin, ear, stomach/gut, or bladder infection while taking Prolia. Tell your doctor if you develop signs of infection, such as:

Tell your doctor if your experience serious side effects of Prolia including jaw pain, new or unusual thigh/hip/groin pain, or bone/joint/muscle pain.

What is Evista?

Evista (raloxifene hydrochloride) is an estrogen agonist/antagonist used to treat or prevent osteoporosis in postmenopausal women. Evista is also used to reduce the risk of invasive breast cancer in postmenopausal women who have osteoporosis or who are otherwise at risk of invasive breast cancer.

What is Prolia?

Prolia (denosumab) is a monoclonal antibody used to treat bone loss (osteoporosis) in women who are at high risk for bone fracture after menopause.

QUESTION

What is another medical term for osteoporosis? See Answer

What Drugs Interact With Evista?

Evista may interact with cholestyramine, blood thinners, diazepam, diazoxide, birth control pills or hormone replacement therapy.

What Drugs Interact With Prolia?

Prolia may interact with steroids or cancer medicine, cyclosporine, sirolimus, tacrolimus, basiliximab, muromonab-CD3, mycophenolate mofetil, azathioprine, leflunomide, or etanercept.

How Should Evista Be Taken?

The recommended dosage is one 60 mg Evista tablet daily, taken any time of day without regard to meals.

How Should Prolia Be Taken?

The dose of Prolia is one 150 mg tablet taken once monthly on the same date each month.

SLIDESHOW

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References
SOURCE:

DailyMed. Evista Product Information.

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fcaaa6dc-74e8-4fb8-800c-5574bf0f8de9

Amgen. Prolia Product Information.

https://www.prolia.com

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