Exservan vs. Radicava

Are Exservan and Radicava the Same Thing?

Exservan (riluzole) and Radicava (edaravone injection) are used to treat amyotrophic lateral sclerosis (ALS).

Exservan and Radicava belong to different drug classes. Exservan is a benzothiazole class drug and Radicava is a central nervous system agent.

Side effects of Exservan that are different from Radicava include oral numbness, weakness/lethargy, nausea, vomiting, decreased lung function, high blood pressure (hypertension), abdominal pain, joint pain, dizziness, dry mouth, insomnia, and itching.

Side effects of Radicava that are different from Exservan include bruising, gait disturbance, headache, skin inflammation or rash, eczema, respiratory failure, respiratory disorder, oxygen deficiency, glucose in the urine, and fungal skin infections (such as ringworm, jock itch, athlete's foot).

Exservan may interact with ciprofloxacin, enoxacin, fluvoxamine, methoxsalen, mexiletine, oral contraceptives, thiabendazole, vemurafenib, zileuton, CYP1A2 inducers, allopurinol, methyldopa, and sulfasalazine.

Radicava may interact with other drugs.

What Are Possible Side Effects of Exservan?

Side effects of Exservan include:

  • ciprofloxacin,
  • enoxacin,
  • fluvoxamine,
  • methoxsalen,
  • mexiletine,
  • oral contraceptives,
  • thiabendazole,
  • vemurafenib,
  • zileuton,
  • CYP1A2 inducers,
  • allopurinol,
  • methyldopa, and
  • sulfasalazine

What Are Possible Side Effects of Radicava?

Common side effects of Radicava include:

  • bruising,
  • gait disturbance,
  • headache,
  • skin inflammation or rash,
  • eczema,
  • respiratory failure,
  • respiratory disorder,
  • oxygen deficiency,
  • glucose in the urine, and
  • fungal skin infections (such as ringworm, jock itch, athlete's foot).

Patients whoto are sensitive to sulfites may have an allergic reaction, including anaphylaxis, to Radicava, which contains sodium bisulfite.

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What Is Exservan?

Exservan (riluzole) is a benzothiazole class drug used to treat amyotrophic lateral sclerosis (ALS).

What Is Radicava?

Radicava (edaravone injection) is an intravenous medication indicated for the treatment of amyotrophic lateral sclerosis (ALS).

What Drugs Interact With Exservan?

Exservan may interact with other medicines such as:

  • ciprofloxacin,
  • enoxacin,
  • fluvoxamine,
  • methoxsalen,
  • mexiletine,
  • oral contraceptives,
  • thiabendazole,
  • vemurafenib,
  • zileuton,
  • CYP1A2 inducers,
  • allopurinol,
  • methyldopa, and
  • sulfasalazine

Tell your doctor all medications and supplements you use and all vaccines you recently received.

What Drugs Interact With Radicava?

Radicava may interact with other drugs.

Tell your doctor all medications and supplements you use.

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How Should Exservan Be Taken?

The recommended dosage of Exservan is 50 mg twice daily, taken at least 1 hour before or 2 hours after a meal.

How Should Radicava Be Taken?

The recommended dosage of Radicava is 60 mg administered as an intravenous infusion over 60 minutes as follows: Initial treatment cycle: daily dosing for 14 days followed by a 14-day drug-free period. Subsequent treatment cycles: daily dosing for 10 days out of 14-day periods, followed by 14-day drug-free periods.

Disclaimer

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Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.

The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.

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References
FDA. Exservan Product Information.

https://www.accessdata.fda.gov/drugsatfda_docs/appletter/2019/212640Orig1s000ltr.pdf

Mitsubishi Tanabe Pharma America. Radicava Product Monograph.

www.radicava.com

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