Medical Editor: John P. Cunha, DO, FACOEP
What Is Factrel?
Factrel (gonadorelin hydrochloride) is a synthetic form of gonadotropin-releasing hormone (GnRH) used to test how well the hypothalamus and pituitary glands are working. The brand name Factrel is discontinued, but generic versions may be available.
What Are Side Effects of Factrel?
Common side effects of Factrel (gonadorelin hydrochloride) include:
- abdominal discomfort
- skin rash, or
- injection site reactions (pain, swelling, or itching)
Factrel may cause serious side effects including:
- difficulty breathing,
- swelling of your face, lips, tongue, or throat,
- flushing (continuing),
- rapid heartbeat,
- hardening of skin at the place of injection,
- itching, pain, redness or swelling of skin at place of injection, and
- skin rash
Get medical help right away, if you have any of the symptoms listed above.
Seek medical care or call 911 at once if you have the following serious side effects:
- Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
- Serious heart symptoms such as fast, irregular, or pounding heartbeats; fluttering in your chest; shortness of breath; and sudden dizziness, lightheartedness, or passing out;
- Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors.
This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.
Dosage for Factrel
The adult dose of Factrel is 100 mcg, administered subcutaneously or intravenously.
What Drugs, Substances, or Supplements Interact with Factrel?
Factrel may interact with other medicines that affect hormone levels in the body. Tell your doctor all medications and supplements you use.
Factrel During Pregnancy or Breastfeeding
Factrel is not expected to be harmful to a fetus. Tell your doctor if you are pregnant before receiving this drug. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.
Our Factrel (gonadorelin hydrochloride) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Systemic effects have been reported rarely following administration of 100 mcg of Factrel (gonadorelin) .
CNS: headache, light-headedness.
Dermatologic: local swelling, occasionally with pain and pruritis, at the injection site may occur following subcutaneous administration; local and generalized skin rash have been noted after chronic subcutaneous administration.
Rare instances of hypersensitivity reaction (bronchospasm, tachycardia, flushing, urticaria, induration at injection site) and anaphylactic reactions have been reported following multiple-dose administration.
Read the entire FDA prescribing information for Factrel (Gonadorelin)
© Factrel Patient Information is supplied by Cerner Multum, Inc. and Factrel Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.
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