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Last reviewed on RxList: 12/28/2016
Factrel Side Effects Center

Last reviewed on RxList 4/8/2016

Factrel (gonadorelin hydrochloride) is a synthetic form of gonadotropin-releasing hormone (GnRH) used to test how well the hypothalamus and pituitary glands are working. The brand name Factrel is discontinued, but generic versions may be available. Common side effects of Factrel (gonadorelin hydrochloride) include:

  • headache
  • flushing
  • nausea
  • abdominal discomfort
  • dizziness
  • lightheadedness
  • skin rash, or
  • injection site reactions (pain, swelling, or itching)

The adult dose of Factrel is 100 mcg, administered subcutaneously or intravenously. Factrel may interact with other medicines that affect hormone levels in the body. Tell your doctor all medications and supplements you use. Factrel is not expected to be harmful to a fetus. Tell your doctor if you are pregnant before receiving this drug. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

Our Factrel (gonadorelin hydrochloride) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Factrel Professional Information


Systemic effects have been reported rarely following administration of 100 mcg of Factrel (gonadorelin) .

CNS:   headache, light-headedness.

GI:   nausea, abdominal discomfort.

Dermatologic:   local swelling, occasionally with pain and pruritis, at the injection site may occur following subcutaneous administration; local and generalized skin rash have been noted after chronic subcutaneous administration.

Cardiovascular:   flushing.

Rare instances of hypersensitivity reaction (bronchospasm, tachycardia, flushing, urticaria, induration at injection site) and anaphylactic reactions have been reported following multiple-dose administration.

There has been a report of pituitary apoplexy and sudden blindness following gonadotropin-releasing hormone administration to a patient with a gonadotropin-secreting adenoma.


Read the entire FDA prescribing information for Factrel (Gonadorelin)

Related Resources for Factrel

© Factrel Patient Information is supplied by Cerner Multum, Inc. and Factrel Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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