Medical Editor: John P. Cunha, DO, FACOEP
- stomach pain,
- feeling full,
- hair loss,
- muscle weakness,
- ringing in your ears,
- sleep problems (insomnia),
- vomiting, or
- loss of appetite.
Tell your doctor if you have serious side effects of Fansidar including:
- the first sign of any skin rash, no matter how mild;
- a severe blistering, peeling, and red skin rash;
- pale skin, easy bruising or bleeding;
- feeling tired, weak, or dizzy;
- hallucinations, seizure (convulsions);
- urinating less than usual or not at all;
- jaundice (yellowing of the skin or eyes); or
- fever, chills, sore throat, swollen tongue, joint pain, cough, or feeling short of breath.
The recommended dosage of Fansidar is 1 tablet once a week for adults. Dosage for children is based upon body weight. Talk to your doctor about your individual dosage recommendation. Fansidar may interact with other anti-malaria medications, chloroquine, or sulfa drugs. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant during treatment with Fansidar; it may harm a fetus. Malaria is more likely to cause death in a pregnant woman. If you are pregnant, talk with your doctor about the risks of traveling to areas where malaria is common. Fansidar is not recommended for use while breastfeeding.
Our Fansidar (sulfadoxine and pyrimethamine) Tablets Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the entire patient information overview for Fansidar (Sulfadoxine and Pyrimethamine)
For completeness, all major reactions to sulfonamides and to pyrimethamine are included below, even though they may not have been reported with Fansidar (see WARNINGS and PRECAUTIONS: Information For The Patient).
Skin and Miscellaneous Sites Allergic Reactions
Erythema multiforme, Stevens-Johnson syndrome, generalized skin eruptions, toxic epidermal necrolysis, urticaria, serum sickness, pruritus, exfoliative dermatitis, anaphylactoid reactions, periorbital edema, conjunctival and scleral injection, photosensitization, arthralgia, allergic myocarditis, slight hair loss, Lyell's syndrome,
Central Nervous System Reactions
Drug fever, chills, periarteritis nodosa and LE phenomenon have occurred.
The sulfonamides bear certain chemical similarities to some goitrogens, diuretics (acetazolamide and the thiazides), and oral hypoglycemic agents. Diuresis and hypoglycemia have occurred rarely in patients receiving sulfonamides. Cross-sensitivity may exist with these agents. Rats appear to be especially susceptible to the goitrogenic effects of sulfonamides, and long-term administration has produced thyroid malignancies in the species.
Read the entire FDA prescribing information for Fansidar (Sulfadoxine and Pyrimethamine)