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Fasenra vs. Advair

Reviewed on 11/12/2019

Are Fasenra and Advair the Same Thing?

Fasenra (benralizumab) injection and Advair Diskus (fluticasone and salmeterol oral inhaler) are used to treat asthma.

Advair Diskus is also used to treat chronic bronchitis, including COPD associated with chronic bronchitis. Advair Diskus is used in patients whose symptoms are not adequately controlled on a long-term asthma control medication, since one of the active ingredients in salmeterol is LABA, which has been linked to asthma-related deaths. Advair Diskus should not be used to treat acute episodes of asthma or COPD.

Fasenra and Advair Diskus belong to different drug classes. Fasenra is an interleukin-5 receptor alpha-directed cytolytic monoclonal antibody (IgG1, kappa) and Advair Diskus is a combination of a corticosteroid and a beta2-adrenergic bronchodilator.

Side effects of Fasenra and Advair Diskus that are similar include headache and sore throat.

Side effects of Fasenra that are different from Advair Diskus include fever, hypersensitivity reactions, and injection site reactions (pain, redness, itching, or a small lump).

Side effects of Advair Diskus that are different from Fasenra include upper respiratory tract infections, dizziness, nausea, vomiting, stomach upset, diarrhea, yeast infections of the mouth or throat (oral thrush), dry mouth/nose/throat, stuffy nose, sinus pain, cough, sore throat, hoarseness or deepened voice, and musculoskeletal pain.

Fasenra may interact with other drugs.

Advair Diskus may interact with amiodarone, diuretics (water pills), HIV medicines, MAO inhibitors, antidepressants, antibiotics, antifungal medications, and beta-blockers.

SLIDESHOW

What Is Asthma? Symptoms, Causes, and Treatments See Slideshow

What Are Possible Side Effects of Fasenra?

Common side effects of Fasenra include:

  • headache,
  • sore throat,
  • fever,
  • hypersensitivity reactions, and
  • injection site reactions (pain, redness, itching, or a small lump)

What Are Possible Side Effects of Advair?

Common side effects of Advair include:

  • upper respiratory tract infections,
  • headaches,
  • dizziness,
  • nausea,
  • vomiting,
  • stomach upset,
  • diarrhea,
  • yeast infections of the mouth or throat (oral thrush),
  • sore throat,
  • dry mouth/nose/throat,
  • stuffy nose,
  • sinus pain,
  • cough,
  • sore throat,
  • hoarseness or deepened voice, and
  • musculoskeletal pain.

What Is Fasenra?

Fasenra (benralizumab) injection is an interleukin-5 receptor alpha-directed cytolytic monoclonal antibody (IgG1, kappa) indicated for the add-on maintenance treatment of patients with severe asthma aged 12 years and older, and with an eosinophilic phenotype.

What Is Advair?

Advair Diskus (fluticasone and salmeterol oral inhaler) is a combination of a corticosteroid and a beta2-adrenergic bronchodilator used to treat asthma and chronic bronchitis, including COPD associated with chronic bronchitis. Advair Diskus is used in patients whose symptoms are not adequately controlled on a long-term asthma control medication, since one of the active ingredients in salmeterol is LABA, which has been linked to asthma-related deaths. Advair Diskus should not be used to treat acute episodes of asthma or COPD. Advair Diskus is available in generic form.

What Drugs Interact With Fasenra?

Fasenra may interact with other drugs. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant before using Fasenra; it is unknown how it would affect a fetus. Monoclonal antibodies such as Fasenra are transported across the placenta during the third trimester of pregnancy; therefore, potential effects on a fetus are likely to be greater during the third trimester of pregnancy. It is unknown if Fasenra passes into breast milk or how it would affect a nursing infant. Consult your doctor before breastfeeding.

What Drugs Interact With Advair?

Advair may interact with amiodarone, diuretics (water pills), HIV medicines, MAO inhibitors, antidepressants, antibiotics, or beta-blockers

How Should Fasenra Be Taken?

Are Fasenra and Advair the Same Thing?

Fasenra (benralizumab) injection and Advair Diskus (fluticasone and salmeterol oral inhaler) are used to treat asthma.

Advair Diskus is also used to treat chronic bronchitis, including COPD associated with chronic bronchitis. Advair Diskus is used in patients whose symptoms are not adequately controlled on a long-term asthma control medication, since one of the active ingredients in salmeterol is LABA, which has been linked to asthma-related deaths. Advair Diskus should not be used to treat acute episodes of asthma or COPD.

Fasenra and Advair Diskus belong to different drug classes. Fasenra is an interleukin-5 receptor alpha-directed cytolytic monoclonal antibody (IgG1, kappa) and Advair Diskus is a combination of a corticosteroid and a beta2-adrenergic bronchodilator.

Side effects of Fasenra and Advair Diskus that are similar include headache and sore throat.

Side effects of Fasenra that are different from Advair Diskus include fever, hypersensitivity reactions, and injection site reactions (pain, redness, itching, or a small lump).

Side effects of Advair Diskus that are different from Fasenra include upper respiratory tract infections, dizziness, nausea, vomiting, stomach upset, diarrhea, yeast infections of the mouth or throat (oral thrush), dry mouth/nose/throat, stuffy nose, sinus pain, cough, sore throat, hoarseness or deepened voice, and musculoskeletal pain.

Fasenra may interact with other drugs.

Advair Diskus may interact with amiodarone, diuretics (water pills), HIV medicines, MAO inhibitors, antidepressants, antibiotics, antifungal medications, and beta-blockers.

QUESTION

Asthma is a chronic respiratory disease. See Answer

What Are Possible Side Effects of Fasenra?

Common side effects of Fasenra include:

  • headache,
  • sore throat,
  • fever,
  • hypersensitivity reactions, and
  • injection site reactions (pain, redness, itching, or a small lump)

What Are Possible Side Effects of Advair?

Common side effects of Advair include:

  • nausea,
  • vomiting,
  • stomach pain,
  • diarrhea,
  • headache,
  • dizziness,
  • depression,
  • joint pain,
  • trouble sleeping,
  • strange dreams,
  • back pain,
  • itching or skin rash,
  • changes in the color of skin on your palms or soles of your feet, or
  • changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist).

Tell your doctor if you have serious side effects of Advair including:

  • mental/mood changes (such as depression, anxiety),
  • loss of appetite,
  • stomach or abdominal pain,
  • pink or bloody urine, or
  • changes in the amount of urine.

What Is Fasenra?

Fasenra (benralizumab) injection is an interleukin-5 receptor alpha-directed cytolytic monoclonal antibody (IgG1, kappa) indicated for the add-on maintenance treatment of patients with severe asthma aged 12 years and older, and with an eosinophilic phenotype.

What Is Advair?

Advair (emtricitabine/tenofovir disoproxil fumarate) is a combination of antiviral drugs used to treat HIV, which causes acquired immunodeficiency syndrome (AIDS). Advair is not a cure for HIV or AIDS.

What Drugs Interact With Fasenra?

Fasenra may interact with other drugs. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant before using Fasenra; it is unknown how it would affect a fetus. Monoclonal antibodies such as Fasenra are transported across the placenta during the third trimester of pregnancy; therefore, potential effects on a fetus are likely to be greater during the third trimester of pregnancy. It is unknown if Fasenra passes into breast milk or how it would affect a nursing infant. Consult your doctor before breastfeeding.

What Drugs Interact With Advair?

Advair may interact with lithium, methotrexate, pain or arthritis medicines, medicines used to prevent organ transplant rejection, IV antibiotics, antiviral medicines, cancer medicines, herpes medications, medications to treat cytomegalovirus (CMV), or other HIV medicines. Tell your doctor all medications and supplements you use. During pregnancy, Advair should be used only when prescribed. It is normal to prescribe HIV medicines such as Advair for pregnant women with HIV. This can decrease the risk of passing HIV to the baby. Advair may be part of that treatment. Consult your doctor. It is unknown if Advair passes into breast milk. Because breast milk can transmit HIV, do not breastfeed.

How Should Fasenra Be Taken?

The dose of Fasenra is one tablet taken orally once daily with or without food.

How Should Advair Be Taken?

The recommended dose of Fasenra is 30 mg every 4 weeks for the first 3 doses, followed by once every 8 weeks thereafter.

How Should Advair Be Taken?

For patients aged 12 years and older, the dosage of Advair Diskus is 1 inhalation twice daily, approximately 12 hours apart.

Disclaimer

All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA). 

Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.

Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs. 

The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.

As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current. 

Any missing drug warnings or information does not in any way guarantee the safety, effectiveness, or the lack of adverse effects of any drug. The drug information provided is intended for reference only and should not be used as a substitute for medical advice.    

If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information.

You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.

Disclaimer

All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA).

Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.

Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.

The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.

As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current.

Any missing drug warnings or information does not in any way guarantee the safety, effectiveness, or the lack of adverse effects of any drug. The drug information provided is intended for reference only and should not be used as a substitute for medical advice.

If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information.

You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.

References
AstraZeneca. Fasenra Product Monograph.

https://www.fasenra.com

GSK. Advair Drug Information.

https://www.advair.com/

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