NINTEDANIB - ORAL

USER REVIEWS

Comment from: Gma 65-74 Transgender 1 to 6 months Caregiver Published: March 01

Never had heart problems.After 3 months of taking ofev I got congestive heart failure. I was taken off ofev. Also had loss of taste.

Related Reading: ofev | congestive heart failure

Comment from: Gma 65-74 Transgender 1 to 6 months Caregiver Published: March 01

Never had heart problems.After 3 months of taking ofev I got congestive heart failure. I was taken off ofev. Also had loss of taste.

Related Reading: ofev | congestive heart failure

Comment from: Ray P 55-64 Transgender 1 to 6 months Caregiver Published: February 08

Three weeks after starting I began seeing my overall fatigue level increase and I saw my shortness of breath increase. So much to the point that after 3 months I would be out of breath just getting up for work and getting dressed. Have stopped it now hoping to get back to where I was. I was working out regular and walking 2 miles about 3 days a week before. Now i'm lucky to get 1 mile without taking a break half way

SLIDESHOW

COPD Foods to Boost Your Health - COPD Diet Tips See Slideshow
Comment from: Gma 65-74 Transgender 1 to 6 months Caregiver Published: March 01

Never had heart problems.After 3 months of taking ofev I got congestive heart failure. I was taken off ofev. Also had loss of taste.

Related Reading: ofev | congestive heart failure

Comment from: Ray P 55-64 Transgender 1 to 6 months Caregiver Published: February 08

Three weeks after starting I began seeing my overall fatigue level increase and I saw my shortness of breath increase. So much to the point that after 3 months I would be out of breath just getting up for work and getting dressed. Have stopped it now hoping to get back to where I was. I was working out regular and walking 2 miles about 3 days a week before. Now i'm lucky to get 1 mile without taking a break half way

Comment from: Patrick 45-54 Transgender 1 to 6 months Caregiver Published: September 06

I have been taking this medication for 5 months after a while it caused severe diarrhoea I was nearly ready to quit however I have found taking one Imodium each morning and eating a banana with both doses as well as taking a broad spectrum Probiotic daily has really helped and the diarrhoea has stopped completely I’m very happy now I would recommend anyone with diarrhoea to try this

Related Reading: imodium

Comment from: Gma 65-74 Transgender 1 to 6 months Caregiver Published: March 01

Never had heart problems.After 3 months of taking ofev I got congestive heart failure. I was taken off ofev. Also had loss of taste.

Related Reading: ofev | congestive heart failure

Comment from: Ray P 55-64 Transgender 1 to 6 months Caregiver Published: February 08

Three weeks after starting I began seeing my overall fatigue level increase and I saw my shortness of breath increase. So much to the point that after 3 months I would be out of breath just getting up for work and getting dressed. Have stopped it now hoping to get back to where I was. I was working out regular and walking 2 miles about 3 days a week before. Now i'm lucky to get 1 mile without taking a break half way

Comment from: Patrick 45-54 Transgender 1 to 6 months Caregiver Published: September 06

I have been taking this medication for 5 months after a while it caused severe diarrhoea I was nearly ready to quit however I have found taking one Imodium each morning and eating a banana with both doses as well as taking a broad spectrum Probiotic daily has really helped and the diarrhoea has stopped completely I’m very happy now I would recommend anyone with diarrhoea to try this

Related Reading: imodium

Comment from: michael 65-74 Transgender 1 to 6 months Caregiver Published: September 06

today is 9-6-2021, still having diahrea after stopping use. used from 4-18-2021 to 5-20-2021. not a happy camper

QUESTION

COPD (chronic obstructive pulmonary disease) is the same as adult-onset asthma. See Answer
Comment from: Gma 65-74 Transgender 1 to 6 months Caregiver Published: March 01

Never had heart problems.After 3 months of taking ofev I got congestive heart failure. I was taken off ofev. Also had loss of taste.

Related Reading: ofev | congestive heart failure

Comment from: Ray P 55-64 Transgender 1 to 6 months Caregiver Published: February 08

Three weeks after starting I began seeing my overall fatigue level increase and I saw my shortness of breath increase. So much to the point that after 3 months I would be out of breath just getting up for work and getting dressed. Have stopped it now hoping to get back to where I was. I was working out regular and walking 2 miles about 3 days a week before. Now i'm lucky to get 1 mile without taking a break half way

Comment from: Patrick 45-54 Transgender 1 to 6 months Caregiver Published: September 06

I have been taking this medication for 5 months after a while it caused severe diarrhoea I was nearly ready to quit however I have found taking one Imodium each morning and eating a banana with both doses as well as taking a broad spectrum Probiotic daily has really helped and the diarrhoea has stopped completely I’m very happy now I would recommend anyone with diarrhoea to try this

Related Reading: imodium

Comment from: michael 65-74 Transgender 1 to 6 months Caregiver Published: September 06

today is 9-6-2021, still having diahrea after stopping use. used from 4-18-2021 to 5-20-2021. not a happy camper

Comment from: Linda 65-74 Female 6 months to less than 1 year Patient Published: December 29

Been on for 8 mos. Was very slow progression until started Ofev. All symptoms are much worse, cough breathlessness, etc. Not slowing it down. Nauseated all the time. I question this drug & am stopping taking it.

Related Reading: ofev

Comment from: Gma 65-74 Transgender 1 to 6 months Caregiver Published: March 01

Never had heart problems.After 3 months of taking ofev I got congestive heart failure. I was taken off ofev. Also had loss of taste.

Related Reading: ofev | congestive heart failure

Comment from: Ray P 55-64 Transgender 1 to 6 months Caregiver Published: February 08

Three weeks after starting I began seeing my overall fatigue level increase and I saw my shortness of breath increase. So much to the point that after 3 months I would be out of breath just getting up for work and getting dressed. Have stopped it now hoping to get back to where I was. I was working out regular and walking 2 miles about 3 days a week before. Now i'm lucky to get 1 mile without taking a break half way

Comment from: Patrick 45-54 Transgender 1 to 6 months Caregiver Published: September 06

I have been taking this medication for 5 months after a while it caused severe diarrhoea I was nearly ready to quit however I have found taking one Imodium each morning and eating a banana with both doses as well as taking a broad spectrum Probiotic daily has really helped and the diarrhoea has stopped completely I’m very happy now I would recommend anyone with diarrhoea to try this

Related Reading: imodium

Comment from: michael 65-74 Transgender 1 to 6 months Caregiver Published: September 06

today is 9-6-2021, still having diahrea after stopping use. used from 4-18-2021 to 5-20-2021. not a happy camper

Comment from: Linda 65-74 Female 6 months to less than 1 year Patient Published: December 29

Been on for 8 mos. Was very slow progression until started Ofev. All symptoms are much worse, cough breathlessness, etc. Not slowing it down. Nauseated all the time. I question this drug & am stopping taking it.

Related Reading: ofev

Comment from: Linda 65-74 Female 6 months to less than 1 year Patient Published: December 29

My PF had been progressing very slowly over years. Was put on Ofev & all symptoms got worse, cough, breathlessness, etc. Feel nauseated most of time. Has not slowed it down. I Question this drug & will stop taking.

Related Reading: ofev

Comment from: Gma 65-74 Transgender 1 to 6 months Caregiver Published: March 01

Never had heart problems.After 3 months of taking ofev I got congestive heart failure. I was taken off ofev. Also had loss of taste.

Related Reading: ofev | congestive heart failure

Comment from: Ray P 55-64 Transgender 1 to 6 months Caregiver Published: February 08

Three weeks after starting I began seeing my overall fatigue level increase and I saw my shortness of breath increase. So much to the point that after 3 months I would be out of breath just getting up for work and getting dressed. Have stopped it now hoping to get back to where I was. I was working out regular and walking 2 miles about 3 days a week before. Now i'm lucky to get 1 mile without taking a break half way

Comment from: Patrick 45-54 Transgender 1 to 6 months Caregiver Published: September 06

I have been taking this medication for 5 months after a while it caused severe diarrhoea I was nearly ready to quit however I have found taking one Imodium each morning and eating a banana with both doses as well as taking a broad spectrum Probiotic daily has really helped and the diarrhoea has stopped completely I’m very happy now I would recommend anyone with diarrhoea to try this

Related Reading: imodium

Comment from: michael 65-74 Transgender 1 to 6 months Caregiver Published: September 06

today is 9-6-2021, still having diahrea after stopping use. used from 4-18-2021 to 5-20-2021. not a happy camper

Comment from: Linda 65-74 Female 6 months to less than 1 year Patient Published: December 29

Been on for 8 mos. Was very slow progression until started Ofev. All symptoms are much worse, cough breathlessness, etc. Not slowing it down. Nauseated all the time. I question this drug & am stopping taking it.

Related Reading: ofev

Comment from: Linda 65-74 Female 6 months to less than 1 year Patient Published: December 29

My PF had been progressing very slowly over years. Was put on Ofev & all symptoms got worse, cough, breathlessness, etc. Feel nauseated most of time. Has not slowed it down. I Question this drug & will stop taking.

Related Reading: ofev

Comment from: Liz Beth 65-74 Female 1 to 6 months Patient Published: January 04

PF for many years. On OFEV for two months. All of the side effects, no discernable benefit. Made me feel horrible, gave me bad diarreah, nausea, side pain. Discontinued use. Spoke to OFEV directly, they agree it does not help breathing at all, it only slows down the progression of the disease. Useless when my breathing is so bad. Who wants tolive longer like this.

Related Reading: ofev

Comment from: Gma 65-74 Transgender 1 to 6 months Caregiver Published: March 01

Never had heart problems.After 3 months of taking ofev I got congestive heart failure. I was taken off ofev. Also had loss of taste.

Related Reading: ofev | congestive heart failure

Comment from: Ray P 55-64 Transgender 1 to 6 months Caregiver Published: February 08

Three weeks after starting I began seeing my overall fatigue level increase and I saw my shortness of breath increase. So much to the point that after 3 months I would be out of breath just getting up for work and getting dressed. Have stopped it now hoping to get back to where I was. I was working out regular and walking 2 miles about 3 days a week before. Now i'm lucky to get 1 mile without taking a break half way

Comment from: Patrick 45-54 Transgender 1 to 6 months Caregiver Published: September 06

I have been taking this medication for 5 months after a while it caused severe diarrhoea I was nearly ready to quit however I have found taking one Imodium each morning and eating a banana with both doses as well as taking a broad spectrum Probiotic daily has really helped and the diarrhoea has stopped completely I’m very happy now I would recommend anyone with diarrhoea to try this

Related Reading: imodium

Comment from: michael 65-74 Transgender 1 to 6 months Caregiver Published: September 06

today is 9-6-2021, still having diahrea after stopping use. used from 4-18-2021 to 5-20-2021. not a happy camper

Comment from: Linda 65-74 Female 6 months to less than 1 year Patient Published: December 29

Been on for 8 mos. Was very slow progression until started Ofev. All symptoms are much worse, cough breathlessness, etc. Not slowing it down. Nauseated all the time. I question this drug & am stopping taking it.

Related Reading: ofev

Comment from: Linda 65-74 Female 6 months to less than 1 year Patient Published: December 29

My PF had been progressing very slowly over years. Was put on Ofev & all symptoms got worse, cough, breathlessness, etc. Feel nauseated most of time. Has not slowed it down. I Question this drug & will stop taking.

Related Reading: ofev

Comment from: Liz Beth 65-74 Female 1 to 6 months Patient Published: January 04

PF for many years. On OFEV for two months. All of the side effects, no discernable benefit. Made me feel horrible, gave me bad diarreah, nausea, side pain. Discontinued use. Spoke to OFEV directly, they agree it does not help breathing at all, it only slows down the progression of the disease. Useless when my breathing is so bad. Who wants tolive longer like this.

Related Reading: ofev

Comment from: roxy6 65-74 Female 1 to 6 months Patient Published: December 17

Seven weeks on Ofev for Pulmonary Fibrosis. All of the side effects (feel generally horrible; back and abdominal pains, dirreah), no benefit so far. I may be too far gone for help. Have had PF for years.

Related Reading: ofev | pulmonary fibrosis

Comment from: Gma 65-74 Transgender 1 to 6 months Caregiver Published: March 01

Never had heart problems.After 3 months of taking ofev I got congestive heart failure. I was taken off ofev. Also had loss of taste.

Related Reading: ofev | congestive heart failure

Comment from: Ray P 55-64 Transgender 1 to 6 months Caregiver Published: February 08

Three weeks after starting I began seeing my overall fatigue level increase and I saw my shortness of breath increase. So much to the point that after 3 months I would be out of breath just getting up for work and getting dressed. Have stopped it now hoping to get back to where I was. I was working out regular and walking 2 miles about 3 days a week before. Now i'm lucky to get 1 mile without taking a break half way

Comment from: Patrick 45-54 Transgender 1 to 6 months Caregiver Published: September 06

I have been taking this medication for 5 months after a while it caused severe diarrhoea I was nearly ready to quit however I have found taking one Imodium each morning and eating a banana with both doses as well as taking a broad spectrum Probiotic daily has really helped and the diarrhoea has stopped completely I’m very happy now I would recommend anyone with diarrhoea to try this

Related Reading: imodium

Comment from: michael 65-74 Transgender 1 to 6 months Caregiver Published: September 06

today is 9-6-2021, still having diahrea after stopping use. used from 4-18-2021 to 5-20-2021. not a happy camper

Comment from: Linda 65-74 Female 6 months to less than 1 year Patient Published: December 29

Been on for 8 mos. Was very slow progression until started Ofev. All symptoms are much worse, cough breathlessness, etc. Not slowing it down. Nauseated all the time. I question this drug & am stopping taking it.

Related Reading: ofev

Comment from: Linda 65-74 Female 6 months to less than 1 year Patient Published: December 29

My PF had been progressing very slowly over years. Was put on Ofev & all symptoms got worse, cough, breathlessness, etc. Feel nauseated most of time. Has not slowed it down. I Question this drug & will stop taking.

Related Reading: ofev

Comment from: Liz Beth 65-74 Female 1 to 6 months Patient Published: January 04

PF for many years. On OFEV for two months. All of the side effects, no discernable benefit. Made me feel horrible, gave me bad diarreah, nausea, side pain. Discontinued use. Spoke to OFEV directly, they agree it does not help breathing at all, it only slows down the progression of the disease. Useless when my breathing is so bad. Who wants tolive longer like this.

Related Reading: ofev

Comment from: roxy6 65-74 Female 1 to 6 months Patient Published: December 17

Seven weeks on Ofev for Pulmonary Fibrosis. All of the side effects (feel generally horrible; back and abdominal pains, dirreah), no benefit so far. I may be too far gone for help. Have had PF for years.

Related Reading: ofev | pulmonary fibrosis

Comment from: Ranger1 55-64 Male 6 months to less than 1 year Patient Published: June 10

I was diagnosed with IPF in August of 2018 and after taking prednisone for a bit my Dr switched me Ofev. I've been on this therapy for a while now and according to my pulmonary Dr my lungs have not worsened although they are stable for now.

Related Reading: prednisone | ofev

Comment from: Gma 65-74 Transgender 1 to 6 months Caregiver Published: March 01

Never had heart problems.After 3 months of taking ofev I got congestive heart failure. I was taken off ofev. Also had loss of taste.

Related Reading: ofev | congestive heart failure

Comment from: Ray P 55-64 Transgender 1 to 6 months Caregiver Published: February 08

Three weeks after starting I began seeing my overall fatigue level increase and I saw my shortness of breath increase. So much to the point that after 3 months I would be out of breath just getting up for work and getting dressed. Have stopped it now hoping to get back to where I was. I was working out regular and walking 2 miles about 3 days a week before. Now i'm lucky to get 1 mile without taking a break half way

Comment from: Patrick 45-54 Transgender 1 to 6 months Caregiver Published: September 06

I have been taking this medication for 5 months after a while it caused severe diarrhoea I was nearly ready to quit however I have found taking one Imodium each morning and eating a banana with both doses as well as taking a broad spectrum Probiotic daily has really helped and the diarrhoea has stopped completely I’m very happy now I would recommend anyone with diarrhoea to try this

Related Reading: imodium

Comment from: michael 65-74 Transgender 1 to 6 months Caregiver Published: September 06

today is 9-6-2021, still having diahrea after stopping use. used from 4-18-2021 to 5-20-2021. not a happy camper

Comment from: Linda 65-74 Female 6 months to less than 1 year Patient Published: December 29

Been on for 8 mos. Was very slow progression until started Ofev. All symptoms are much worse, cough breathlessness, etc. Not slowing it down. Nauseated all the time. I question this drug & am stopping taking it.

Related Reading: ofev

Comment from: Linda 65-74 Female 6 months to less than 1 year Patient Published: December 29

My PF had been progressing very slowly over years. Was put on Ofev & all symptoms got worse, cough, breathlessness, etc. Feel nauseated most of time. Has not slowed it down. I Question this drug & will stop taking.

Related Reading: ofev

Comment from: Liz Beth 65-74 Female 1 to 6 months Patient Published: January 04

PF for many years. On OFEV for two months. All of the side effects, no discernable benefit. Made me feel horrible, gave me bad diarreah, nausea, side pain. Discontinued use. Spoke to OFEV directly, they agree it does not help breathing at all, it only slows down the progression of the disease. Useless when my breathing is so bad. Who wants tolive longer like this.

Related Reading: ofev

Comment from: roxy6 65-74 Female 1 to 6 months Patient Published: December 17

Seven weeks on Ofev for Pulmonary Fibrosis. All of the side effects (feel generally horrible; back and abdominal pains, dirreah), no benefit so far. I may be too far gone for help. Have had PF for years.

Related Reading: ofev | pulmonary fibrosis

Comment from: Ranger1 55-64 Male 6 months to less than 1 year Patient Published: June 10

I was diagnosed with IPF in August of 2018 and after taking prednisone for a bit my Dr switched me Ofev. I've been on this therapy for a while now and according to my pulmonary Dr my lungs have not worsened although they are stable for now.

Related Reading: prednisone | ofev

Comment from: Lee 65-74 Female 1 to 6 months Caregiver Published: April 06

I am a 65 year old male diagnosed with LUPUS and IPF.I have been on all the other drugs used to teat both and OFEV is my last option.I have been taking it about 6 months now and have gotten worst but not sure if progression has slowed or accelerated.I have been loosing muscle mass but not sure if it is from OFEV.I am suppose to use supplemental O2 but still working and push myself beyond limits maybe I shouldn't.Not a sitter and OFEV does cause me extra fatigue,some diarrhea,raised my blood pressure and causes me to have loss of appetite and periods of headaches.Having LUPUS flareups and IPF it is hard to tell if medication or disease are the cause.Only option left for me is lung transplant which I have already told my DR's is not an option I would do.God bless to all and hope this helps others.

Related Reading: lupus | ofev | diarrhea

SLIDESHOW

COPD Foods to Boost Your Health - COPD Diet Tips See Slideshow
Comment from: Marathon Man 55-64 Female less than 1 month Patient Published: December 24

I have Lung Fibrosis caused by a prescription medication. So not exactly IPF. Age:63. Previous health: Excellent . I started on Pirfenidone (Esbriet) and a 2 month trial of high-dose steroids. They were tolerable, but did nothing objectively, according to the PFT tests, so I was switched to OFEV about a month ago. It was OK for the first two weeks, but now I have no appetite, a bit of weight loss, loss of energy, fleeting nausea, loose stools, bloating, general malaise and occasional right sided headache. That is hard to chalk up to pure chance. And my cough is worse then last month (on Pirfenidone), so I may have to go back to Pirfenidone.I have to rate this drug (OFEV) as barely tolerable and of unknown effect on my lung fibrosis after brief use. IF I KNEW that it was slowing the fibrois, I would be more willing to adapt to OFEV. Looks like Lung Transplant for me, if I am eligible. I cling to HOPE.

Related Reading: esbriet | ofev | headache

Comment from: Marathon Man 55-64 Female less than 1 month Patient Published: December 24

I have Lung Fibrosis caused by a prescription medication. So not exactly IPF. Age:63. Previous health: Excellent . I started on Pirfenidone (Esbriet) and a 2 month trial of high-dose steroids. They were tolerable, but did nothing objectively, according to the PFT tests, so I was switched to OFEV about a month ago. It was OK for the first two weeks, but now I have no appetite, a bit of weight loss, loss of energy, fleeting nausea, loose stools, bloating, general malaise and occasional right sided headache. That is hard to chalk up to pure chance. And my cough is worse then last month (on Pirfenidone), so I may have to go back to Pirfenidone.I have to rate this drug (OFEV) as barely tolerable and of unknown effect on my lung fibrosis after brief use. IF I KNEW that it was slowing the fibrois, I would be more willing to adapt to OFEV. Looks like Lung Transplant for me, if I am eligible. I cling to HOPE.

Related Reading: esbriet | ofev | headache

Comment from: 55-64 Female 6 months to less than 1 year Patient Published: May 17

I have been diagnosed with IPF, fortunately early in the disease progression. I was on Esbriet, and it caused severe fatigue for me. My pulmonologist switched me to OFEV, and I feel MUCH better. Minimal side effects. Lung functions have been stable for 6 months. I'm so glad I have the opportunity to take something that may extend my life and my healthy years!

Related Reading: esbriet | ofev

Comment from: Marathon Man 55-64 Female less than 1 month Patient Published: December 24

I have Lung Fibrosis caused by a prescription medication. So not exactly IPF. Age:63. Previous health: Excellent . I started on Pirfenidone (Esbriet) and a 2 month trial of high-dose steroids. They were tolerable, but did nothing objectively, according to the PFT tests, so I was switched to OFEV about a month ago. It was OK for the first two weeks, but now I have no appetite, a bit of weight loss, loss of energy, fleeting nausea, loose stools, bloating, general malaise and occasional right sided headache. That is hard to chalk up to pure chance. And my cough is worse then last month (on Pirfenidone), so I may have to go back to Pirfenidone.I have to rate this drug (OFEV) as barely tolerable and of unknown effect on my lung fibrosis after brief use. IF I KNEW that it was slowing the fibrois, I would be more willing to adapt to OFEV. Looks like Lung Transplant for me, if I am eligible. I cling to HOPE.

Related Reading: esbriet | ofev | headache

Comment from: 55-64 Female 6 months to less than 1 year Patient Published: May 17

I have been diagnosed with IPF, fortunately early in the disease progression. I was on Esbriet, and it caused severe fatigue for me. My pulmonologist switched me to OFEV, and I feel MUCH better. Minimal side effects. Lung functions have been stable for 6 months. I'm so glad I have the opportunity to take something that may extend my life and my healthy years!

Related Reading: esbriet | ofev

Comment from: J.B. 55-64 Female 1 to 6 months Patient Published: December 20

Diagnosed with pulmonary fibrosis in July of 2015. Treated with steroids....no problems. M.D. changed me to Ofev in July 2016, Was still taking a low dose of Prednisone at the time. Once I stopped the Prednisone. The mild diarrhea became much worse. Then came the loss of appetite and weight loss. Became very weak with muscle and joint pain. I sleep on a wedge anyhow, acid reflux terrible, abdominal pain, fatigue, my cough got worse, nausea and vomiting with no warning. Decided I couldn't take any more. I no longer had quality of life. Stopped it. Within two day my appetite was back, I was less fatigued, no nausea, no diarrhea, no vomiting and my cough was better. Tired of being a guinea pig.

Related Reading: pulmonary fibrosis | ofev | prednisone

Comment from: Marathon Man 55-64 Female less than 1 month Patient Published: December 24

I have Lung Fibrosis caused by a prescription medication. So not exactly IPF. Age:63. Previous health: Excellent . I started on Pirfenidone (Esbriet) and a 2 month trial of high-dose steroids. They were tolerable, but did nothing objectively, according to the PFT tests, so I was switched to OFEV about a month ago. It was OK for the first two weeks, but now I have no appetite, a bit of weight loss, loss of energy, fleeting nausea, loose stools, bloating, general malaise and occasional right sided headache. That is hard to chalk up to pure chance. And my cough is worse then last month (on Pirfenidone), so I may have to go back to Pirfenidone.I have to rate this drug (OFEV) as barely tolerable and of unknown effect on my lung fibrosis after brief use. IF I KNEW that it was slowing the fibrois, I would be more willing to adapt to OFEV. Looks like Lung Transplant for me, if I am eligible. I cling to HOPE.

Related Reading: esbriet | ofev | headache

Comment from: 55-64 Female 6 months to less than 1 year Patient Published: May 17

I have been diagnosed with IPF, fortunately early in the disease progression. I was on Esbriet, and it caused severe fatigue for me. My pulmonologist switched me to OFEV, and I feel MUCH better. Minimal side effects. Lung functions have been stable for 6 months. I'm so glad I have the opportunity to take something that may extend my life and my healthy years!

Related Reading: esbriet | ofev

Comment from: J.B. 55-64 Female 1 to 6 months Patient Published: December 20

Diagnosed with pulmonary fibrosis in July of 2015. Treated with steroids....no problems. M.D. changed me to Ofev in July 2016, Was still taking a low dose of Prednisone at the time. Once I stopped the Prednisone. The mild diarrhea became much worse. Then came the loss of appetite and weight loss. Became very weak with muscle and joint pain. I sleep on a wedge anyhow, acid reflux terrible, abdominal pain, fatigue, my cough got worse, nausea and vomiting with no warning. Decided I couldn't take any more. I no longer had quality of life. Stopped it. Within two day my appetite was back, I was less fatigued, no nausea, no diarrhea, no vomiting and my cough was better. Tired of being a guinea pig.

Related Reading: pulmonary fibrosis | ofev | prednisone

Comment from: Texsardo 55-64 Female 1 to 6 months Patient Published: September 09

Diagnosed Jan 2016. Started OFEV almost 3 months ago. Age 64, at 170, b/p avg 105/64 . Working, I don't know yet. Absolutely no side effect's. I think general health and weight my be causing some side effects for others. I'm trying to stay healthy enough to kick IPF's butt.

Related Reading: ofev

Comment from: Marathon Man 55-64 Female less than 1 month Patient Published: December 24

I have Lung Fibrosis caused by a prescription medication. So not exactly IPF. Age:63. Previous health: Excellent . I started on Pirfenidone (Esbriet) and a 2 month trial of high-dose steroids. They were tolerable, but did nothing objectively, according to the PFT tests, so I was switched to OFEV about a month ago. It was OK for the first two weeks, but now I have no appetite, a bit of weight loss, loss of energy, fleeting nausea, loose stools, bloating, general malaise and occasional right sided headache. That is hard to chalk up to pure chance. And my cough is worse then last month (on Pirfenidone), so I may have to go back to Pirfenidone.I have to rate this drug (OFEV) as barely tolerable and of unknown effect on my lung fibrosis after brief use. IF I KNEW that it was slowing the fibrois, I would be more willing to adapt to OFEV. Looks like Lung Transplant for me, if I am eligible. I cling to HOPE.

Related Reading: esbriet | ofev | headache

Comment from: 55-64 Female 6 months to less than 1 year Patient Published: May 17

I have been diagnosed with IPF, fortunately early in the disease progression. I was on Esbriet, and it caused severe fatigue for me. My pulmonologist switched me to OFEV, and I feel MUCH better. Minimal side effects. Lung functions have been stable for 6 months. I'm so glad I have the opportunity to take something that may extend my life and my healthy years!

Related Reading: esbriet | ofev

Comment from: J.B. 55-64 Female 1 to 6 months Patient Published: December 20

Diagnosed with pulmonary fibrosis in July of 2015. Treated with steroids....no problems. M.D. changed me to Ofev in July 2016, Was still taking a low dose of Prednisone at the time. Once I stopped the Prednisone. The mild diarrhea became much worse. Then came the loss of appetite and weight loss. Became very weak with muscle and joint pain. I sleep on a wedge anyhow, acid reflux terrible, abdominal pain, fatigue, my cough got worse, nausea and vomiting with no warning. Decided I couldn't take any more. I no longer had quality of life. Stopped it. Within two day my appetite was back, I was less fatigued, no nausea, no diarrhea, no vomiting and my cough was better. Tired of being a guinea pig.

Related Reading: pulmonary fibrosis | ofev | prednisone

Comment from: Texsardo 55-64 Female 1 to 6 months Patient Published: September 09

Diagnosed Jan 2016. Started OFEV almost 3 months ago. Age 64, at 170, b/p avg 105/64 . Working, I don't know yet. Absolutely no side effect's. I think general health and weight my be causing some side effects for others. I'm trying to stay healthy enough to kick IPF's butt.

Related Reading: ofev

Comment from: Jimbo 55-64 Female less than 1 month Patient Published: August 16

Started taking Esbriet in a 2014 trial. My IPF progressed to a point where my doc changed to OFEV (Aug. 2016)to see if it would work better Esbriet was 9 pills a day (267 milligrams) Ofev is 2 pills 150 mg. Esbriet would put me to sleep after about 30 minutes. With OFEV the only side effect I have is a rash which I treat with Benedryl. Maybe Esbriet works? maybe Ofev works? we do what we can, but It is really just in God's hands. My prayers to all who suffer with IPF.

Related Reading: esbriet | ofev

Comment from: Marathon Man 55-64 Female less than 1 month Patient Published: December 24

I have Lung Fibrosis caused by a prescription medication. So not exactly IPF. Age:63. Previous health: Excellent . I started on Pirfenidone (Esbriet) and a 2 month trial of high-dose steroids. They were tolerable, but did nothing objectively, according to the PFT tests, so I was switched to OFEV about a month ago. It was OK for the first two weeks, but now I have no appetite, a bit of weight loss, loss of energy, fleeting nausea, loose stools, bloating, general malaise and occasional right sided headache. That is hard to chalk up to pure chance. And my cough is worse then last month (on Pirfenidone), so I may have to go back to Pirfenidone.I have to rate this drug (OFEV) as barely tolerable and of unknown effect on my lung fibrosis after brief use. IF I KNEW that it was slowing the fibrois, I would be more willing to adapt to OFEV. Looks like Lung Transplant for me, if I am eligible. I cling to HOPE.

Related Reading: esbriet | ofev | headache

Comment from: 55-64 Female 6 months to less than 1 year Patient Published: May 17

I have been diagnosed with IPF, fortunately early in the disease progression. I was on Esbriet, and it caused severe fatigue for me. My pulmonologist switched me to OFEV, and I feel MUCH better. Minimal side effects. Lung functions have been stable for 6 months. I'm so glad I have the opportunity to take something that may extend my life and my healthy years!

Related Reading: esbriet | ofev

Comment from: J.B. 55-64 Female 1 to 6 months Patient Published: December 20

Diagnosed with pulmonary fibrosis in July of 2015. Treated with steroids....no problems. M.D. changed me to Ofev in July 2016, Was still taking a low dose of Prednisone at the time. Once I stopped the Prednisone. The mild diarrhea became much worse. Then came the loss of appetite and weight loss. Became very weak with muscle and joint pain. I sleep on a wedge anyhow, acid reflux terrible, abdominal pain, fatigue, my cough got worse, nausea and vomiting with no warning. Decided I couldn't take any more. I no longer had quality of life. Stopped it. Within two day my appetite was back, I was less fatigued, no nausea, no diarrhea, no vomiting and my cough was better. Tired of being a guinea pig.

Related Reading: pulmonary fibrosis | ofev | prednisone

Comment from: Texsardo 55-64 Female 1 to 6 months Patient Published: September 09

Diagnosed Jan 2016. Started OFEV almost 3 months ago. Age 64, at 170, b/p avg 105/64 . Working, I don't know yet. Absolutely no side effect's. I think general health and weight my be causing some side effects for others. I'm trying to stay healthy enough to kick IPF's butt.

Related Reading: ofev

Comment from: Jimbo 55-64 Female less than 1 month Patient Published: August 16

Started taking Esbriet in a 2014 trial. My IPF progressed to a point where my doc changed to OFEV (Aug. 2016)to see if it would work better Esbriet was 9 pills a day (267 milligrams) Ofev is 2 pills 150 mg. Esbriet would put me to sleep after about 30 minutes. With OFEV the only side effect I have is a rash which I treat with Benedryl. Maybe Esbriet works? maybe Ofev works? we do what we can, but It is really just in God's hands. My prayers to all who suffer with IPF.

Related Reading: esbriet | ofev

Comment from: barbie 75 or over Female less than 1 month Patient Published: August 15

placed on drug by lung specialist after 3 weeks taken off due to constant bathroom trips Passing out dizziness weakness Ofev reversed the charge to blue cross for second prescription and non effectiveness and patients request

Related Reading: dizziness | ofev

Comment from: Marathon Man 55-64 Female less than 1 month Patient Published: December 24

I have Lung Fibrosis caused by a prescription medication. So not exactly IPF. Age:63. Previous health: Excellent . I started on Pirfenidone (Esbriet) and a 2 month trial of high-dose steroids. They were tolerable, but did nothing objectively, according to the PFT tests, so I was switched to OFEV about a month ago. It was OK for the first two weeks, but now I have no appetite, a bit of weight loss, loss of energy, fleeting nausea, loose stools, bloating, general malaise and occasional right sided headache. That is hard to chalk up to pure chance. And my cough is worse then last month (on Pirfenidone), so I may have to go back to Pirfenidone.I have to rate this drug (OFEV) as barely tolerable and of unknown effect on my lung fibrosis after brief use. IF I KNEW that it was slowing the fibrois, I would be more willing to adapt to OFEV. Looks like Lung Transplant for me, if I am eligible. I cling to HOPE.

Related Reading: esbriet | ofev | headache

Comment from: 55-64 Female 6 months to less than 1 year Patient Published: May 17

I have been diagnosed with IPF, fortunately early in the disease progression. I was on Esbriet, and it caused severe fatigue for me. My pulmonologist switched me to OFEV, and I feel MUCH better. Minimal side effects. Lung functions have been stable for 6 months. I'm so glad I have the opportunity to take something that may extend my life and my healthy years!

Related Reading: esbriet | ofev

Comment from: J.B. 55-64 Female 1 to 6 months Patient Published: December 20

Diagnosed with pulmonary fibrosis in July of 2015. Treated with steroids....no problems. M.D. changed me to Ofev in July 2016, Was still taking a low dose of Prednisone at the time. Once I stopped the Prednisone. The mild diarrhea became much worse. Then came the loss of appetite and weight loss. Became very weak with muscle and joint pain. I sleep on a wedge anyhow, acid reflux terrible, abdominal pain, fatigue, my cough got worse, nausea and vomiting with no warning. Decided I couldn't take any more. I no longer had quality of life. Stopped it. Within two day my appetite was back, I was less fatigued, no nausea, no diarrhea, no vomiting and my cough was better. Tired of being a guinea pig.

Related Reading: pulmonary fibrosis | ofev | prednisone

Comment from: Texsardo 55-64 Female 1 to 6 months Patient Published: September 09

Diagnosed Jan 2016. Started OFEV almost 3 months ago. Age 64, at 170, b/p avg 105/64 . Working, I don't know yet. Absolutely no side effect's. I think general health and weight my be causing some side effects for others. I'm trying to stay healthy enough to kick IPF's butt.

Related Reading: ofev

Comment from: Jimbo 55-64 Female less than 1 month Patient Published: August 16

Started taking Esbriet in a 2014 trial. My IPF progressed to a point where my doc changed to OFEV (Aug. 2016)to see if it would work better Esbriet was 9 pills a day (267 milligrams) Ofev is 2 pills 150 mg. Esbriet would put me to sleep after about 30 minutes. With OFEV the only side effect I have is a rash which I treat with Benedryl. Maybe Esbriet works? maybe Ofev works? we do what we can, but It is really just in God's hands. My prayers to all who suffer with IPF.

Related Reading: esbriet | ofev

Comment from: barbie 75 or over Female less than 1 month Patient Published: August 15

placed on drug by lung specialist after 3 weeks taken off due to constant bathroom trips Passing out dizziness weakness Ofev reversed the charge to blue cross for second prescription and non effectiveness and patients request

Related Reading: dizziness | ofev

Comment from: 55-64 Male 1 to 6 months Patient Published: May 30

I was diagnosed 12/2015 and have been taking Ofev for 4 months. efficacy unknown; maybe a fresh CT scan will tell. Fatigue and mild diarrhea.

Related Reading: ofev | diarrhea

Comment from: Sid 65-74 Female less than 1 month Patient Published: May 14

I'm in my third week of taking Ofev, 150mg 2XDay. I was diagnosed with IPF in 2009. Put on Oxy then. My last CT scan (Jul 2015) indicated honeycombing had started. I was hesitant to start a new med that was fast tracked to the market that offered no cure. I finally agreed to start recently, three weeks now. I've had the terrible side effects that everyone describes. I can't imagine existing in life where I stay on the toilet about the same amount of time I sit in my recliner. That's about all I'm able to do now. I'm calling my doctor Monday to let him know I won't be needing a refill.

Related Reading: ofev

Comment from: Sid 65-74 Female less than 1 month Patient Published: May 14

I'm in my third week of taking Ofev, 150mg 2XDay. I was diagnosed with IPF in 2009. Put on Oxy then. My last CT scan (Jul 2015) indicated honeycombing had started. I was hesitant to start a new med that was fast tracked to the market that offered no cure. I finally agreed to start recently, three weeks now. I've had the terrible side effects that everyone describes. I can't imagine existing in life where I stay on the toilet about the same amount of time I sit in my recliner. That's about all I'm able to do now. I'm calling my doctor Monday to let him know I won't be needing a refill.

Related Reading: ofev

Comment from: breathegood 35-44 Male 6 months to less than 1 year Patient Published: March 04

I have IPF, and I have been on this stuff since it was released by the FDA. TIPS from a career troubleshooter: - If you are not skinny yet, get there. I lost 100lb on the 30/10 diet and it made a gigantic difference in my breathing! - You have to take Ofev with a decent meal. - You need to have 12hrs between doses or you better be close to a bathroom. - Sleep on a wedge pillow to avoid acid reflux. Who knows if it's working. I just thought I would share what I have learned. Avoiding ALL acidic foods like tomatoes, because acid re-flux could be the cause of IPF?

Related Reading: ofev

Comment from: Sid 65-74 Female less than 1 month Patient Published: May 14

I'm in my third week of taking Ofev, 150mg 2XDay. I was diagnosed with IPF in 2009. Put on Oxy then. My last CT scan (Jul 2015) indicated honeycombing had started. I was hesitant to start a new med that was fast tracked to the market that offered no cure. I finally agreed to start recently, three weeks now. I've had the terrible side effects that everyone describes. I can't imagine existing in life where I stay on the toilet about the same amount of time I sit in my recliner. That's about all I'm able to do now. I'm calling my doctor Monday to let him know I won't be needing a refill.

Related Reading: ofev

Comment from: breathegood 35-44 Male 6 months to less than 1 year Patient Published: March 04

I have IPF, and I have been on this stuff since it was released by the FDA. TIPS from a career troubleshooter: - If you are not skinny yet, get there. I lost 100lb on the 30/10 diet and it made a gigantic difference in my breathing! - You have to take Ofev with a decent meal. - You need to have 12hrs between doses or you better be close to a bathroom. - Sleep on a wedge pillow to avoid acid reflux. Who knows if it's working. I just thought I would share what I have learned. Avoiding ALL acidic foods like tomatoes, because acid re-flux could be the cause of IPF?

Related Reading: ofev

Comment from: Steve 55-64 Male 6 months to less than 1 year Caregiver Published: November 12

I was diagnosed with IPF about 3 years ago and I've been taking OFEV for about 6 months now.I too have the fatigue and sometimes some slight stomach irritation. I dont feel any better but ive been told by my Dr. the only real way to know if its working is by having current Pulmonary tests compared to past tests. The manufacturer showed very promising results from their own tests-many patients showed the rate of disease progression cut by 50%. There's no promise by the makers of a cure or 'improvement' other than the possibility of slowing the progression of the disease-IE getting sicker slower.Bear in mind there is NOTHING else out there for medicinal treatment of Pulmonary Fibrosis except Ofev (nintedanib) and their competitors Esbriet (pirfenidone). So the way I see it if this is my only chance of living longer (short of a lung transplant) ill take it.

Related Reading: ofev | stomach | treatment

References
Medical Editor: John P. Cunha, DO, FACOEP

Health Solutions From Our Sponsors