Fetroja vs. Keflex

Are Keflex and Fetroja the Same Thing?

Fetroja (cefiderocol) and Keflex (cephalexin) are cephalosporin antibiotics used to treat urinary tract infections (UTIs).

Fetroja is used for the treatment of complicated urinary tract infections (cUTI), including pyelonephritis caused by susceptible Gram-negative microorganisms.

Keflex is also used to treat various other bacterial infections, and before dental procedures in patients identified with certain heart-related conditions to prevent bacterial infections of the heart known as endocarditis.

Side effects of Fetroja and Keflex that are similar include diarrhea, rash, headache, nausea, and vomiting.

Side effects of Fetroja that are different from Keflex include infusion site reactions, constipation, candidiasis (oral thrush or vaginal yeast infections), cough, elevations in liver tests, and low blood potassium (hypokalemia).

Side effects of Keflex that are different from Fetroja include dizziness, tiredness, stomach upset, abdominal pain, joint pain, vaginal itching or discharge, itching, and swelling.

Fetroja may interact with other drugs.

Keflex may interact with blood thinners, metformin, and probenecid.

SLIDESHOW

Urinary Incontinence in Women: Types, Causes, and Treatments for Bladder Control See Slideshow

What Are Possible Side Effects of Fetroja?

Common side effects of Fetroja include:

  • diarrhea,
  • infusion site reactions,
  • constipation,
  • rash,
  • candidiasis (oral thrush or vaginal yeast infections),
  • cough,
  • elevations in liver tests,
  • headache,
  • low blood potassium (hypokalemia),
  • nausea, and
  • vomiting

What Are Possible Side Effects of Keflex?

Common side effects of Keflex include:

  • diarrhea,
  • dizziness,
  • tiredness,
  • headache,
  • stomach upset,
  • abdominal pain,
  • joint pain,
  • vaginal itching or discharge,
  • nausea,
  • vomiting,
  • itching,
  • swelling, and
  • rash.

What is Fetroja?

Fetroja (cefiderocol) is a cephalosporin antibacterial used to treat patients 18 years of age or older who have limited or no alternative treatment options, for the treatment of complicated urinary tract infections (cUTI), including pyelonephritis caused by susceptible Gram-negative microorganisms.

What is Keflex?

Keflex (cephalexin) is a cephalosporin antibiotic prescribed to treat bacterial infections. Keflex is also used before dental procedures in patients identified with certain heart-related conditions to prevent bacterial infections of the heart known as endocarditis. Keflex is available as a generic drug.

QUESTION

How much urine does the average adult pass each day? See Answer

What Drugs Interact With Fetroja?

Fetroja may interact with other medicines.

Tell your doctor all medications and supplements you use.

What Drugs Interact With Keflex?

Keflex and amoxicillin may interact with probenecid and blood thinners.

Keflex may also interact with metformin.

How Should Fetroja Be Taken?

The dose of Fetroja for injection is 2 grams administered every 8 hours by intravenous (IV) infusion over 3 hours in patients with creatinine clearance (CLcr) 60 to 119 mL/min.

How Should Keflex Be Taken?

Keflex dosage depends on the condition being treated. Keflex should be used with caution in patients who have kidney disease and those who report a history of penicillin allergy.

Disclaimer

All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA).

Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.

Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.

The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.

As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current.

Any missing drug warnings or information does not in any way guarantee the safety, effectiveness, or the lack of adverse effects of any drug. The drug information provided is intended for reference only and should not be used as a substitute for medical advice.

If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information.

You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.

References
FDA. Fetroja Product Information.

https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/209445s000lbl.pdf

FDA. Keflex Product Information.

https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/050405s097lbl.pdf

Health Solutions From Our Sponsors