Fetroja vs. Macrodantin, Macrobid

Are Macrodantin, Macrobid and Fetroja the Same Thing?

Fetroja (cefiderocol) and Macrodantin and Macrobid (nitrofurantoin) are antibiotics used to treat urinary tract infections (UTIs).

Fetroja is used to treat complicated urinary tract infections (cUTI), including pyelonephritis caused by susceptible Gram-negative microorganisms.

Fetroja and Macrodantin and Macrobid are different types of antibiotics. Fetroja is a cephalosporin antibiotic and Macrodantin and Macrobid are nitrofuran antibiotics.

Side effects of Fetroja and Macrodantin and Macrobid that are similar include diarrhea, rash, headache, nausea, and vomiting.

Side effects of Fetroja that are different from Macrodantin and Macrobid include infusion site reactions, constipation, candidiasis (oral thrush or vaginal yeast infections), cough, elevations in liver tests, and low blood potassium (hypokalemia).

Side effects of Macrodantin and Macrobid that are different from Fetroja include itching, upset stomach, loss of appetite, rust-colored or brownish urine, and vaginal itching or discharge.

Fetroja may interact with other drugs.

Macrodantin and Macrobid may also interact with antacids, magnesium salicylate, choline magnesium salicylate, and probenecid.

SLIDESHOW

Urinary Incontinence in Women: Types, Causes, and Treatments for Bladder Control See Slideshow

What Are Possible Side Effects of Fetroja?

Common side effects of Fetroja include:

  • diarrhea,
  • infusion site reactions,
  • constipation,
  • rash,
  • candidiasis (oral thrush or vaginal yeast infections),
  • cough,
  • elevations in liver tests,
  • headache,
  • low blood potassium (hypokalemia),
  • nausea, and
  • vomiting

What Are Possible Side Effects of Macrodantin, Macrobid?

Common side effects of Macrodantin, Macrobid include:

  • headache,
  • itching,
  • rash,
  • nausea,
  • upset stomach,
  • vomiting,
  • loss of appetite,
  • diarrhea,
  • rust-colored or brownish urine, or
  • vaginal itching or discharge.

What is Fetroja?

Fetroja (cefiderocol) is a cephalosporin antibacterial used to treat patients 18 years of age or older who have limited or no alternative treatment options, for the treatment of complicated urinary tract infections (cUTI), including pyelonephritis caused by susceptible Gram-negative microorganisms.

What is Macrodantin, Macrobid?

Macrodantin, Macrobid (nitrofurantoin) is an antibiotic prescribed to treat or prevent urinary tract infections. Macrodantin is available in generic form.

QUESTION

How much urine does the average adult pass each day? See Answer

What Drugs Interact With Fetroja?

Fetroja may interact with other medicines.

Tell your doctor all medications and supplements you use.

What Drugs Interact With Macrodantin, Macrobid?

Macrodantin, Macrobid may also interact with magnesium salicylate or choline magnesium salicylate.

How Should Fetroja Be Taken?

The dose of Fetroja for injection is 2 grams administered every 8 hours by intravenous (IV) infusion over 3 hours in patients with creatinine clearance (CLcr) 60 to 119 mL/min.

How Should Macrodantin, Macrobid Be Taken?

Macrodantin, Macrobid should be given with food to improve drug absorption and, in some patients, tolerance. Adults should take 50-100 mg four times a day-the lower dosage level is recommended for uncomplicated urinary tract infections.

Disclaimer

All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA).

Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.

Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.

The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.

As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current.

Any missing drug warnings or information does not in any way guarantee the safety, effectiveness, or the lack of adverse effects of any drug. The drug information provided is intended for reference only and should not be used as a substitute for medical advice.

If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information.

You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.

References
Shionogi. Fetroja Product Information.

https://www.fetroja.com/

DailyMed. Macrodantin Product Information.

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=89d8696b-f9ce-9691-6222-8416ca143bba

Health Solutions From Our Sponsors