Fetroja vs. Rocephin

Reviewed on 8/15/2022

Are Rocephin and Fetroja the Same Thing?

Fetroja (cefiderocol) and Rocephin (ceftriaxone sodium) for Injection are cephalosporin antibiotics used to treat urinary tract infections (UTIs).

  • Fetroja is used to treat complicated urinary tract infections (UTI), including pyelonephritis caused by susceptible Gram-negative microorganisms.
  • Rocephin is also used to treat many kinds of bacterial infections, including severe or life-threatening forms such as meningitis.

Side effects of Fetroja and Rocephin that are similar include diarrhea, injection/infusion site reactions (swelling, redness, pain, a hard lump, or soreness), headache, nausea, and vomiting.

  • Side effects of Fetroja that are different from Rocephin include constipation, rash, candidiasis (oral thrush or vaginal yeast infections), cough, elevations in liver tests, and low blood potassium (hypokalemia).
  • Side effects of Rocephin that are different from Fetroja include loss of appetite, upset stomach, dizziness, overactive reflexes, pain or swelling in the tongue, sweating, and vaginal itching or discharge.

Both Fetroja and Rocephin may interact with other drugs.

QUESTION

How much urine does the average adult pass each day? See Answer

What Are Possible Side Effects of Fetroja?

Common side effects of Fetroja include:

  • diarrhea,
  • infusion site reactions,
  • constipation,
  • rash,
  • candidiasis (oral thrush or vaginal yeast infections),
  • cough,
  • elevations in liver tests,
  • headache,
  • low blood potassium (hypokalemia),
  • nausea, and
  • vomiting

What Are Possible Side Effects of Rocephin?

Common side effects of Rocephin include:

  • injection site reactions (swelling, redness, pain, a hard lump, or soreness),
  • loss of appetite,
  • nausea,
  • vomiting,
  • upset stomach,
  • diarrhea,
  • headache,
  • dizziness,
  • overactive reflexes,
  • pain or swelling in your tongue,
  • sweating, or
  • vaginal itching or discharge.

What is Fetroja?

Fetroja (cefiderocol) is a cephalosporin antibacterial used to treat patients 18 years of age or older who have limited or no alternative treatment options, for the treatment of complicated urinary tract infections (UTI), including pyelonephritis caused by susceptible Gram-negative microorganisms.

What is Rocephin?

Rocephin (ceftriaxone sodium) for Injection is a cephalosporin antibiotic used to treat many kinds of bacterial infections, including severe or life-threatening forms such as meningitis.

Rocephin is available in generic form.

What Drugs Interact With Fetroja?

Fetroja may interact with other medicines. For detailed drug interactions, please visit our Fetroja drug information.

Tell your doctor all medications and supplements you use.

What Drugs Interact With Rocephin?

Rocephin may interact with other drugs. For detailed drug interactions, please visit our Rocephin drug information.

Tell your doctor all medications and supplements you use.

How Should Fetroja Be Taken?

The dose of Fetroja for injection is 2 grams administered every 8 hours by intravenous (IV) infusion over 3 hours in patients with creatinine clearance (CLcr) 60 to 119 mL/min.

How Should Rocephin Be Taken?

The usual adult daily dose is 1 to 2 grams given once a day (or in equally divided doses twice a day) depending on the type and severity of infection.

Pediatric dosing depends on the condition being treated and the child's weight. Other drugs may interact with Rocephin.

SLIDESHOW

Urinary Incontinence in Women: Types, Causes, and Treatments for Bladder Control See Slideshow
Disclaimer

All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA).

Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.

Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.

The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.

As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current.

Any missing drug warnings or information does not in any way guarantee the safety, effectiveness, or the lack of adverse effects of any drug. The drug information provided is intended for reference only and should not be used as a substitute for medical advice.

If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information.

You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.

References
Shionogi. Fetroja Product Information.

https://www.fetroja.com/

Medscape. Rocephin Product Information.

https://reference.medscape.com/drug/rocephin-ceftriaxone-342510

Health Solutions From Our Sponsors