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Fiasp vs. Apidra

Reviewed on 10/30/2019

Are Fiasp and Apidra the Same Thing?

Fiasp (insulin aspart injection) and Apidra (insulin glulisine [rdna origin] inj) are rapid-acting human insulin analogs used to improve glycemic control in adults with diabetes mellitus.

Apidra is also used to improve glycemic control in children who are at least 4 years old with diabetes mellitus. Apidra is usually given together with a long-acting insulin.

Side effects of Fiasp and Apidra that are similar include low blood sugar (hypoglycemia) and injection site reactions (pain, redness, or irritation).

Side effects of Fiasp that are different from Apidra include allergic reactions, hypersensitivity, abnormal distribution of body fat, weight gain, runny or stuffy nose, upper respiratory tract infection, nausea, diarrhea, back pain, and urinary tract infection (UTI).

Both Fiasp and Apidra may interact with alcohol, clonidine, guanethidine, niacin, and reserpine, and beta-blockers.

Fiasp may also interact with antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents (ARBs), disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors (MAOIs), pentoxifylline, pramlintide, salicylates, somatostatin analogs, sulfa drugs, atypical antipsychotics, corticosteroids, danazol, diuretics, estrogens, progestogens, glucagon, isoniazid, oral contraceptives, phenothiazines, protease inhibitors, somatropin, sympathomimetic agents, thyroid hormones, lithium salts, and pentamidine.

Apidra may also interact with albuterol, lanreotide, and octreotide pramlintide. Many other medicines can increase or decrease the effects of Apidra on lowering your blood sugar.

What Are Possible Side Effects of Fiasp?

Common side effects of Fiasp include:

  • low blood sugar (hypoglycemia),
  • allergic reactions,
  • hypersensitivity,
  • injection site reactions,
  • abnormal distribution of body fat,
  • weight gain,
  • runny or stuffy nose,
  • upper respiratory tract infection,
  • nausea, diarrhea,
  • back pain,
  • and urinary tract infection (UTI).

What Are Possible Side Effects of Apidra?

Common side effects of Apidra include:

  • injection site reactions (pain, redness, or irritation).

Apidra can cause low blood sugar (hypoglycemia). Tell your doctor if you experience symptoms of low blood sugar including sudden sweating, shaking (tremor), fast heartbeat, hunger, blurred vision, dizziness, tingling hands/feet, headache, nausea, confusion, drowsiness, weakness, trouble concentrating, confusion, or seizure (convulsions). Tell your doctor if you have serious side effects of Apidra including:

  • signs of low potassium level in the blood (such as muscle cramps, weakness, irregular heartbeat).

What Is Fiasp?

Fiasp (insulin aspart injection) is a rapid-acting human insulin analog indicated to improve glycemic control in adults with diabetes mellitus.

What Is Apidra?

Apidra (insulin glulisine [rdna origin] inj) is a hormone that is produced in the body used to treat diabetes in adults and children who are at least 4 years old. Apidra is usually given together with a long-acting insulin.

QUESTION

Diabetes is defined best as... See Answer

What Drugs Interact With Fiasp?

Fiasp may interact with:

  • antidiabetic agents,
  • ACE inhibitors,
  • angiotensin II receptor blocking agents (ARBs),
  • disopyramide,
  • fibrates,
  • fluoxetine,
  • monoamine oxidase inhibitors (MAOIs),
  • pentoxifylline,
  • pramlintide,
  • salicylates,
  • somatostatin analogs,
  • sulfa drugs,
  • atypical antipsychotics,
  • corticosteroids,
  • danazol,
  • diuretics,
  • estrogens,
  • glucagon,
  • isoniazid,
  • niacin,
  • oral contraceptives,
  • phenothiazines,
  • progestogens,
  • protease inhibitors,
  • somatropin,
  • sympathomimetic agents,
  • thyroid hormones,
  • alcohol,
  • beta-blockers,
  • clonidine,
  • lithium salts,
  • pentamidine,
  • guanethidine,
  • and reserpine.

Tell your doctor all medications and supplements you use.

What Drugs Interact With Apidra?

Apidra may interact with albuterol, clonidine, guanethidine, lanreotide, niacin, octreotide pramlintide, reserpine, or beta-blockers. Many other medicines can increase or decrease the effects of Apidra on lowering your blood sugar. Tell your doctor all prescription and over-the-counter medications and supplements you use. Tell your doctor if you are pregnant before using Apidra. If you are planning pregnancy, discuss a plan for managing your blood sugars with your doctor before you become pregnant. Your doctor may switch the type of insulin you use during pregnancy. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

How Should Fiasp Be Taken?

The dosage of Fiasp is individualized and adjusted based on the route of administration, the individual's metabolic needs, blood glucose monitoring results, and glycemic control goal.

How Should Apidra Be Taken?

The dosage of Apidra is individualized. Blood glucose monitoring is essential. The total daily insulin requirement may vary and is usually between 0.5 to 1 Unit/kg/day.

SLIDESHOW

Diabetes: What Raises and Lowers Your Blood Sugar Level? See Slideshow
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References
Novo Nordisk. Fiasp Drug Information.

https://www.fiasppro.com

Sanofi-Aventis. Apidra Product Information.

https://www.apidra.com/
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