Definition of Fiber FISH

Reviewed on 3/29/2021

Fiber FISH: A cytogenetic (chromosome) laboratory technique in which FISH (fluorescence in situ hybridization) is done on chromosomes that have been mechanically stretched.

Fiber FISH provides a higher resolution of analysis than conventional FISH and yields more precise information as to the localization of a specific DNA probe on the chromosome.

The word "fiber" here refers not to dietary fiber but to a chromosome fiber.

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