Medical Editor: John P. Cunha, DO, FACOEP
What Is Florone?
Florone (diflorasone diacetate cream) is a topical corticosteroid indicated for relief of the inflammatory and itching manifestations of corticosteroid responsive skin conditions.
The brand name Florone (diflorasone diacetate cream) is discontinued, but generic versions may be available.
What Are Side Effects of Florone?
Side effects of Florone include:
- skin burning,
- itching,
- irritation,
- dryness,
- inflamed hair follicles,
- excessive hair growth on the body,
- acne,
- loss of skin color (hypopigmentation),
- sores around the mouth,
- allergic contact dermatitis,
- softening and breakdown of skin,
- secondary infection,
- skin thinning,
- stretch marks,
- sweat rash,
- cataracts,
- glaucoma, and
- fluid accumulation under the retina which can lead to vision loss (central serous chorioretinopathy).
Florone may cause serious side effects including:
- hives,
- difficulty breathing,
- swelling of your face, lips, tongue, or throat,
- swelling,
- weight gain (especially in your face or your upper back and torso),
- irregular menstrual periods,
- changes in sexual function,
- memory problems,
- irritableness,
- blurred vision,
- tunnel vision,
- eye pain,
- seeing halos around lights,
- severe skin irritation where the medication was applied, and
- signs of skin infection (swelling, redness, warmth, oozing)
Get medical help right away, if you have any of the symptoms listed above.
Seek medical care or call 911 at once if you have the following serious side effects:
- Serious eye symptoms such as sudden vision loss, blurred vision,tunnel vision,eye painor swelling, or seeing halos around lights;
- Serious heart symptoms such as fast, irregular, or pounding heartbeats; fluttering in your chest; shortness of breath; and sudden dizziness, lightheartedness, or passing out;
- Severe headache,confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors.
This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.
Dosage for Florone
The dose of topical corticosteroids such as Florone is application to the affected area as a thin film from one to four times daily depending on the severity of the condition.
Florone In Children
The safety and effectiveness of Florone in pediatric patients have not been established.
What Drugs, Substances, or Supplements Interact with Florone?
Florone may interact with other medicines.
Tell your doctor all medications and supplements you use.
Florone During Pregnancy and Breastfeeding
Tell your doctor if you are pregnant or plan to become pregnant before using Florone; drugs of this class should not be used extensively on pregnant patients, in large amounts, or for prolonged periods of time. It is unknown if topical administration of corticosteroids such as Florone could result in sufficient systemic absorption to produce detectable quantities in breast milk. Consult your doctor before breastfeeding.
Additional Information
Our Florone (diflorasone diacetate cream) 0.05% Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

QUESTION
What percentage of the human body is water? See AnswerGet emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Your skin can absorb topical steroid medicine, which may cause steroid side effects throughout the body. Tell your doctor if you have:
- swelling, weight gain (especially in your face or your upper back and torso);
- irregular menstrual periods, changes in sexual function; or
- memory problems, feeling irritable.
Stop using diflorasone topical and call your doctor at once if you have:
- blurred vision, tunnel vision, eye pain, or seeing halos around lights;
- severe skin irritation where the medicine was applied; or
- signs of skin infection (swelling, redness, warmth, oozing).
Steroid medicine can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using this medicine.
Common side effects may include:
- redness or crusting around your hair follicles;
- burning or itching of treated skin;
- lightened color of treated skin;
- skin dryness or irritation;
- acne, skin rash;
- increased hair growth;
- stretch marks; or
- white or "pruned" appearance of the skin (caused by leaving wound dressings on for long periods of time).
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

SLIDESHOW
Sex-Drive Killers: The Causes of Low Libido See SlideshowSIDE EFFECTS
The following adverse reactions have been identified from clinical trials or postmarketing surveillance. Because they are reported from a population from unknown size, it is not always possible to reliably estimate their frequency or establish a causal relationship to topical corticosteroids exposure.
These adverse reactions may occur more frequently with the use of occlusive dressings or prolonged use of topical corticosteroids.
Skin and Subcutaneous Tissue Disorders: burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, skin atrophy, striae, and miliaria
Vision Disorders: cataract, glaucoma, central serous chorioretinopathy
Read the entire FDA prescribing information for Florone (Diflorasone Diacetate Cream)
© Florone Patient Information is supplied by Cerner Multum, Inc. and Florone Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.
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