Medical Editor: John P. Cunha, DO, FACOEP
What Is Fluorescite?
Fluorescite (fluorescein injection) 10% is a diagnostic aid used in diagnostic fluorescein angiography or angioscopy of the retina and iris vasculature. Fluorescite is available in generic form.
What Are Side Effects of Fluorescite?
Common side effects of Fluorescite include:
- nausea,
- vomiting,
- upset stomach,
- headache,
- fainting,
- low blood pressure (hypotension),
- hypersensitivity reactions,
- cardiac arrest,
- shock,
- convulsions,
- injection site reactions (dull aching pain, fluid leakage, blood clots),
- hives,
- itching,
- bronchospasm,
- severe allergic reaction (anaphylaxis), and
- a strong taste in the mouth.
Seek medical care or call 911 at once if you have the following serious side effects:
- Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
- Serious heart symptoms such as fast, irregular, or pounding heartbeats; fluttering in your chest; shortness of breath; and sudden dizziness, lightheartedness, or passing out;
- Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors.
This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.
Dosage for Fluorescite
The normal adult dose of Fluorescite Injection 10% is 500 mg (100 mg/mL) via intravenous administration. For children, the dose should be calculated on the basis of 35 mg for each ten pounds of body weight (7.7 mg/kg body weight).
What Drugs, Substances, or Supplements Interact with Fluorescite?
Fluorescite may interact with other drugs. Tell your doctor all medications and supplements you use.
Fluorescite During Pregnancy or Breastfeeding
During pregnancy, Fluorescite should be used only if prescribed. Fluorescite passes into breast milk. Consult your doctor before breastfeeding.
Additional Information
Our Fluorescite (fluorescein injection) 10% Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

QUESTION
About how much does an adult human brain weigh? See AnswerSIDE EFFECTS
Skin And Urine Discoloration
The most common reaction is temporary yellowish discoloration of the skin and urine. Urine may attain a bright yellow color. Discoloration of the skin usually fades in 6 to 12 hours and usually fades in urine in 24 to 36 hours.
Gastrointestinal Reactions
Nausea, vomiting, and gastrointestinal distress are common adverse events. A strong taste may develop after injection.
Hypersensitivity Reactions
Symptoms and signs of hypersensitivity have occurred. Generalized hives and itching, bronchospasm and anaphylaxis have been reported. Rare cases of death have been reported [see CONTRAINDICATIONS, WARNINGS AND PRECAUTIONS].
Cardiopulmonary Reactions
Cardiac arrest, basilar artery ischemia, severe shock and death may occur rarely.
Neurologic Reactions
Headache may occur. Convulsions and syncope may rarely occur following injection.
Thrombophlebitis
Thrombophlebitis at the injection site has been reported. Extravasation of the solution at the injection site causes intense pain at the site and a dull aching pain in the injected arm [see DOSAGE AND ADMINISTRATION, WARNINGS AND PRECAUTIONS].
DRUG INTERACTIONS
No Information Provided
Read the entire FDA prescribing information for Fluorescite (Fluorescein)

SLIDESHOW
Digestive Disorders: Common Misconceptions See Slideshow© Fluorescite Patient Information is supplied by Cerner Multum, Inc. and Fluorescite Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.
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