Flurandrenolide Topical

Reviewed on 8/23/2022

What Is Flurandrenolide Topical and How Does It Work?

Flurandrenolide Topical is a prescription medication used for the treatment of inflammation and itching caused by skin conditions that respond to steroid medication.

  • Flurandrenolide Topical is available under various brand names: Cordran, Cordran SP, Cordran Tape, Nolix

What Are Side Effects Associated with Using Flurandrenolide Topical?

Common side effects of Flurandrenolide Topical include:

  • burning, itching, or irritation of treated skin;
  • increased hair growth;
  • white or "pruned" appearance of the skin;
  • rash, pimples; or
  • changes in the color of treated skin.

Serious side effects of Flurandrenolide Topical include:

  • hives,
  • difficult breathing,
  • swelling of the face, lips, tongue, or throat.
  • worsening of the skin condition;
  • redness, warmth, swelling, oozing, or severe irritation of any treated skin;
  • high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor; or
  • possible signs of absorbing this medicine through your skin--weight gain (especially in the face or the upper back and torso), slow wound healing, thinning or discolored skin, increased body hair, muscle weakness, nausea, diarrhea, tiredness, mood changes, menstrual changes, sexual changes.

Rare side effects of Flurandrenolide Topical include:

  • none

Seek medical care or call 911 at once if you have the following serious side effects:

  • Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors;
  • Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
  • Serious heart symptoms include fast, irregular, or pounding heartbeats; fluttering in the chest; shortness of breath; sudden dizziness, lightheartedness, or passing out.

This is not a complete list of side effects and other serious side effects or health problems that may occur because of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.

What Are Dosages of the Flurandrenolide Topical?

Adult and pediatric dosage


  • 0.05 %


  • 0.025 %
  • 0.05 %


  • 0.05 %


  • 4 mcg/cm²

Inflammatory/Pruritic Dermatoses

Adult and pediatric dosage

  • Tape: Apply once a day or once every 12 hours
  • Cream/Lotion: Apply once a day to once every 6 hours (typically every 8-12 hours)

Dosage Considerations – Should be Given as Follows: 

  • See “Dosages”

What Other Drugs Interact with Flurandrenolide Topical?

If your medical doctor is using this medicine to treat your pain, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider, or pharmacist first.

  • Flurandrenolide Topical has no noted severe interactions with any other drugs.
  • Flurandrenolide Topical has no noted serious interactions with any other drugs.
  • Flurandrenolide Topical has no noted moderate interactions with any other drugs.
  • Flurandrenolide Topical has no noted minor interactions with any other drugs.

This information does not contain all possible interactions or adverse effects. Visit the RxList Drug Interaction Checker for any drug interactions. Therefore, before using this product, tell your doctor or pharmacist about all your products. Keep a list of all your medications with you and share this information with your doctor and pharmacist. Check with your health care professional or doctor for additional medical advice, or if you have health questions or concerns.

What Are Warnings and Precautions for Flurandrenolide Topical?


  • Allergic to flurandrenolide

Effects of drug abuse

  • None

Short-Term Effects

  • See “What Are Side Effects Associated with Using Diphtheria and tetanus toxoids vaccine?”

Long-Term Effects

  • See “What Are Side Effects Associated with Using Diphtheria and tetanus toxoids vaccine?”


  • Steroid medicines can increase the glucose (sugar) levels in your blood or urine. Tell your doctor if you have diabetes
  • Do not give this medicine to a child without medical advice. Children can absorb larger amounts of this medicine through the skin and may be more likely to have side effects
  • High doses or long-term use of Flurandrenolide Topical can lead to thinning skin, easy bruising, changes in body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.
  • Avoid getting this medicine in your eyes, mouth, or vagina.
  • Do not use Flurandrenolide Topical to treat any skin condition that has not been checked by your doctor.

Pregnancy & Lactation

  • It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
  • Lactation
    • It may not be safe to breastfeed while using this medicine. Ask your doctor about any risks. If you apply flurandrenolide to your chest, avoid areas that may come into contact with the baby's mouth.

Health Solutions From Our Sponsors