Medical Editor: John P. Cunha, DO, FACOEP Last updated on RxList: 2/17/2022
Foltx Side Effects Center

What Is Foltx?

Foltx (folacin, cyanocobalamin & pyridoxine) is a combination of vitamin B-6, vitamin B-12 and folic acid used to treat hyperhomocysteinemia, with particular emphasis for individuals with or at risk for atherosclerotic vascular disease in the coronary, peripheral, or cerebral vessels, or vitamin B-12 deficiency. Foltx is available in generic form.

What Are Side Effects of Foltx?

Common side effects of Foltx include:

  • nausea,
  • stomach upset,
  • diarrhea,
  • drowsiness,
  • flushing,
  • numbness and tingling,
  • headaches,
  • itching,
  • skin rash, or
  • a feeling of swelling of the entire body.

Dosage for Foltx

The usual adult dose of Foltx is one to two tablets daily or as directed by a physician.

What Drugs, Substances, or Supplements Interact with Foltx?

Foltx may interact with altretamine, cisplatin, levodopa (when used without carbidopa), folic acid antagonist (e.g., methotrexate), hydantoins (e.g., phenytoin, diphenylhydantoin), pyrimethamine, or other vitamin/nutritional supplements. Tell your doctor all medications or supplements you are taking.

Foltx During Pregnancy or Breastfeeding

Foltx should be used only when prescribed during pregnancy. This medication passes into breast milk. Consult your doctor before breastfeeding.

Additional Information

Our Foltx (folacin, cyanocobalamin & pyridoxine) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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Foltx Professional Information

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Allergic sensitization has been reported following both oral and parenteral administration of folacin (folic acid). Paresthesia, somnolence, nausea and headaches have been reported with pyridoxine. Mild transient diarrhea, polycythemia vera, itching, transitory exanthema, and the feeling of swelling of the entire body has been associated with cyanocobalamin.

Read the entire FDA prescribing information for Foltx (Folacin, Cyanocobalamin & Pyridoxine)


According to the USDA, there is no difference between a “portion” and a “serving.” See Answer

© Foltx Patient Information is supplied by Cerner Multum, Inc. and Foltx Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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