Definition of Gastric MALT lymphoma

Reviewed on 3/29/2021

Gastric MALT lymphoma: A low-grade malignant lymphoma of the stomach associated with chronic infection by the bacterium H. pylori. Three-quarters of gastric MALT lymphomas regress after the eradication of H. pylori with antibiotics. The one-quarter that are unresponsive to antibiotics carry a characteristic chromosomal translocation or are at an advanced stage. The translocation is of the t(11;18)(q21;q21) type.

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