GlucaGen

Last updated on RxList: 7/17/2018
GlucaGen Side Effects Center

Last reviewed on RxList 7/17/2018

GlucaGen (glucagon [rDNA origin] for injection) is an antihypoglycemic agent used to treat insulin coma or insulin reaction resulting from severe hypoglycemia (low blood sugar). Common side effects of GlucaGen include:

Get medical help immediately if you have any of these signs of an allergic reaction after taking GlucaGen: hives; difficulty breathing; fast or slow heartbeat; swelling of your face, lips, tongue, or throat.

Inject 1 mL dose of GlucaGen (adults and children, weighing more than 55 lbs (25 kg)) or 0.5 mL (children weighing less than 55 lbs (25 kg)) subcutaneously, intramuscularly, or intravenously. If the weight is not known: children younger than 6 years should be given a 0.5 mL and children 6 years and older should be given 1 mL. GlucaGen may interact with insulin, indomethacin, beta-blockers, anticholinergic drugs, or warfarin. Tell your doctor all prescription and over-the-counter mediations and supplements you use. Many other drugs may affect your blood sugar levels. During pregnancy, GlucaGen should be used only when prescribed. It is unknown if this drug passes into breast milk. Though there have been no reports of harm to nursing infants, consult your doctor before breastfeeding.

Our GlucaGen (glucagon [rDNA origin] for injection) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

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GlucaGen Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; fast or slow heartbeat; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of the following skin changes on your face, legs, groin, or genital area:

  • redness;
  • itching;
  • blistering;
  • crusting, scaling; or
  • other skin sores or lesions.

Common side effects may include:

  • nausea, vomiting; or
  • swelling where an injection was given.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for GlucaGen (Glucagon [rDNA origin]) for Injection)

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Diabetes: What Raises and Lowers Your Blood Sugar Level? See Slideshow
GlucaGen Professional Information

SIDE EFFECTS

Side effects may include nausea and vomiting at doses above 1 mg or with rapid injection. Hypotension has been reported up to 2 hours after administration in patients receiving GlucaGen as premedication for upper GI endoscopy procedures. GlucaGen exerts positive inotropic and chronotropic effects and may, therefore, cause tachycardia and hypertension. Adverse reactions indicating toxicity of GlucaGen have not been reported. A temporary increase in both blood pressure and pulse rate may occur following the administration of GlucaGen. Patients taking beta-blockers might be expected to have a greater increase in both pulse and blood pressure, an increase of which will be temporary because of GlucaGen’s short half-life [see DRUG INTERACTIONS]. The increase in blood pressure and pulse rate may require therapy in patients with pheochromocytoma or coronary artery disease [see WARNINGS AND PRECAUTIONS]. Anaphylactic reactions may occur in some cases [see WARNINGS AND PRECAUTIONS].

The following adverse reactions have been identified during postapproval use of GlucaGen. Because these reactions are reported voluntarily from a population of uncertain size, it is generally not possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

Table 1 Frequency of Adverse Reactions

Treatment of severe hypoglycemia
Frequency (%) Adverse Reaction
< 10 Nausea
< 1 Vomiting
Use as a diagnostic aid
< 10 Nausea
< 1 Vomiting
< 1 Hypoglycemia
< 1 Hypoglycemic coma

Read the entire FDA prescribing information for GlucaGen (Glucagon [rDNA origin]) for Injection)

© GlucaGen Patient Information is supplied by Cerner Multum, Inc. and GlucaGen Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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