Gocovri vs. Osmolex ER

Are Gocovri and Osmolex ER the Same Thing?

Gocovri (amantadine extended release capsules) and Osmolex ER (amantadine extended-release tablets) are antivirial and anti-Parkinson drugs used to treat abnormal/involuntary muscle movement (dyskinesia) in patients with Parkinson's disease.

Side effects of Gocovri and Osmolex ER that are similar include hallucinations, dizziness, dry mouth, swelling of extremities, constipation, and dizziness on standing.

Side effects of Gocovri that are different from Osmolex ER include falls.

Side effects of Osmolex ER that are different from Gocovri include nausea, lightheadedness, insomnia, depression, anxiety, irritability, confusion, loss of appetite, loss of coordination, mottled purplish skin discoloration, headache, drowsiness, nervousness, strange dreams, agitation, dry nose, diarrhea, and fatigue.

Both Gocovri and Osmolex ER may interact with other anticholinergic drugs, with drugs affecting urinary pH (e.g., carbonic anhydrase inhibitors, sodium bicarbonate), alcohol, and "live" vaccines.

Gocovri may also interact with carbonic anhydrase inhibitors.

What Are Possible Side Effects of Gocovri?

Common side effects of Gocovri include:

Other side effects of Gocovri include:

What Are Possible Side Effects of Osmolex ER?

Common side effects of Osmolex ER include:

  • nausea,
  • dizziness,
  • lightheadedness,
  • insomnia,
  • depression,
  • anxiety and irritability,
  • hallucinations,
  • confusion,
  • loss of appetite,
  • dry mouth,
  • constipation,
  • loss of coordination,
  • mottled purplish skin discoloration,
  • swelling of extremities,
  • dizziness on standing,
  • headache,
  • drowsiness,
  • nervousness,
  • strange dreams,
  • agitation,
  • dry nose,
  • diarrhea,
  • and fatigue

What Is Gocovri?

Gocovri (amantadine extended release capsules) is an antivirial and anti-Parkinson drug indicated for the treatment of dyskinesia in patients with Parkinson's disease receiving levodopa-based therapy, with or without concomitant dopaminergic medications.

What Is Osmolex ER?

Osmolex ER (amantadine extended-release tablets) is indicated for the treatment of drug-induced extrapyramidal reactions in adult patients with Parkinson's disease.

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What Drugs Interact With Gocovri?

Gocovri may interact with other anticholinergic drugs, carbonic anhydrase inhibitors, sodium bicarbonate, alcohol, and “live” vaccines. Tell your doctor all medications and supplements you use and all vaccines you recently received. Gocovri is not recommended for use during pregnancy; it may harm a fetus. Gocovri passes into breast milk but its effect on nursing infants is unknown. Gocovri may alter breast milk production or excretion. Consult your doctor before breastfeeding.

What Drugs Interact With Osmolex ER?

Osmolex ER may interact with anticholinergic drugs, drugs affecting urinary pH (e.g., carbonic anhydrase inhibitors, sodium bicarbonate), live influenza vaccines, and alcohol. Tell your doctor all medications and supplements you use. Osmolex ER is not recommended for use during pregnancy; it may harm a fetus. Osmolex ER passes into breast milk but its effects on nursing infants is unknown. Consult your doctor before breastfeeding.

How Should Gocovri Be Taken?

The initial daily dosage of Gocovri is 137 mg, administered orally once daily at bedtime. After one week, increase to the recommended dosage of 274 mg (two 137 mg capsules) once daily at bedtime.

How Should Osmolex ER Be Taken?

The initial dosage of Osmolex ER is 129 mg orally once daily in the morning. The dosage may be increased in weekly intervals to a maximum daily dose of 322 mg once daily in the morning.

QUESTION

Parkinson's disease is only seen in people of advanced age. See Answer
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References
Adamas Pharmaceuticals, Inc. Gocovri Product Information.

https://www.gocovri.com

Vertical Pharmaceuticals, LLC. Osmolex ER Prescribing Information.

www.osmolexhcp.com/?

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