Reviewed on 6/11/2021
Other Name(s):

Annona cherimola, Annona macrocarpa, Annona muricata, Brazilian Cherimoya, Brazilian Paw Paw, Corossol, Corossol Épineux, Corossolier, Durian Benggala, Guanabana, Guanavana, Nangka Blanda, Nangka Londa, Soursop, Sour Sop, Toge-Banreisi.


Graviola is a small evergreen tree. The leaves, fruit, seeds, and stem are used to make medicine.

Despite safety concerns, graviola is used to treat infections caused by bacteria and parasites including leishmaniasis, a disease caused by parasites transmitted through the bite of sand fleas; herpes; coughs; and cancer. It is also used to cause vomiting and to empty the bowels. Some people use graviola to help them relax.

Graviola is applied to the skin for arthritis.

In foods, graviola is used in cooking and beverages.

How does it work?

Graviola contains many chemicals that may be active against cancer, as well as disease-causing agents such as bacteria, viruses, and parasites.


Next to red peppers, you can get the most vitamin C from ________________. See Answer

Uses & Effectiveness

Insufficient Evidence to Rate Effectiveness for...

  • Cancer. There is evidence that some of the chemicals in graviola may keep cancer cells from removing anticancer drugs. This may help the drugs work better. Some chemicals in graviola may also kill cancer cells directly.
  • Bacterial infections.
  • Parasitic infections.
  • Coughs.
  • Inflammation of the nose and throat.
  • Herpes.
  • An infection caused by sand fleas (leishmaniasis).
  • Causing relaxation.
  • Causing vomiting.
  • Emptying the bowels.
  • Other conditions.
More evidence is needed to rate the effectiveness of graviola for these uses.

Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).

Side Effects

Graviola is UNSAFE. It can kill nerve cells in the brain and other parts of the body. It may cause movement disorders similar to Parkinson’s disease.

Special Precautions & Warnings:

Pregnancy or breast-feeding: Do not use graviola. It is UNSAFE.

Parkinson’s disease: Graviola might make the symptoms of Parkinson’s disease worse.


Vitamin D Deficiency: How Much Vitamin D Is Enough? See Slideshow


The appropriate dose of graviola depends on several factors such as the user’s age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for graviola. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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