Grifulvin V Side Effects Center

Last updated on RxList: 10/11/2021
Grifulvin V Side Effects Center

What Is Grifulvin V?

Grifulvin V (griseofulvin microsize) is an antifungal medication used to treat fungal infections of the skin, hair, and nails such as jock itch, athlete's foot, and barber's itch. Grifulvin V is available in generic form.

What Are Side Effects of Grifulvin V?

Common side effects of Grifulvin V include:

  • headache,
  • nausea,
  • vomiting,
  • diarrhea,
  • stomach upset,
  • tiredness,
  • dizziness, or
  • trouble sleeping (insomnia),
  • flushing (warmth, redness, or tingly feeling),
  • confusion,
  • numbness or tingling in your hands or feet, or
  • menstrual irregularities.

Tell your doctor if you have unlikely but serious side effects of Grifulvin V including:

  • mental/mood changes (e.g., confusion, trouble doing normal activities),
  • sunburn-like rash,
  • hearing changes,
  • butterfly-shaped facial rash (around the nose and cheeks), or
  • joint or muscle pain.

Dosage for Grifulvin V

The recommended adult daily dose of Grifulvin V is 500 mg for tinea corporis, tinea cruris, and tinea capitis. For fungus infections more difficult to eradicate such as tinea pedis and tinea unguium, a daily dose of 1 g is recommended. Pediatric dosage is based on the child's weight.

What Drugs, Substances, or Supplements Interact with Grifulvin V?

Grifulvin V may interact with blood thinners, birth control pills, aspirin and other salicylates, or cyclosporine. Tell your doctor all medications you use.

Grifulvin V During Pregnancy or Breastfeeding

Grifulvin V is not recommended for use during pregnancy. It may harm a fetus. Birth control is recommended during treatment and for 1 month after the drug is stopped. If you are planning to become pregnant within 1 month after treatment, the manufacturer recommends avoiding this drug. The effects of this drug on human sperm are unknown. The manufacturer recommends waiting for a period of time after completing treatment before trying to father a child. Consult your doctor. It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.

Additional Information

Our Grifulvin V (griseofulvin microsize) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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Grifulvin V Consumer Information

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Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Call your doctor at once if you have:

  • numbness, tingling, or burning pain in your hands or feet;
  • confusion, trouble with daily activities;
  • fever, chills, flu symptoms, white patches or sores inside your mouth or throat;
  • liver problems--loss of appetite, stomach pain (upper right side), dark urine, jaundice (yellowing of the skin or eyes);
  • kidney problems--little or no urination, swelling in your feet or ankles, feeling tired or short of breath, foamy urine;
  • lupus-like symptoms--muscle or joint pain, flu symptoms, chest pain, and a rash or patchy skin color that worsens in sunlight; or
  • signs of stomach bleeding--bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds.

Common side effects may include:

  • nausea, vomiting, upset stomach, diarrhea;
  • headache, tiredness;
  • rash;
  • sleep problems (insomnia); or
  • dizziness.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Grifulvin V (Griseofulvin Microsize)


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Grifulvin V Professional Information


When adverse reactions occur, they are most commonly of the hypersensitivity type such as skin rashes, urticaria and rarely, angioneurotic edema or erythema multiforme-like drug reaction, and may necessitate withdrawal of therapy and appropriate countermeasures. Paresthesias of the hands and feet have been reported rarely after extended therapy. Other side effects reported occasionally are oral thrush, nausea, vomiting, epigastric distress, diarrhea, headache, fatigue, dizziness, insomnia, mental confusion and impairment of performance of routine activities.

Proteinuria and leukopenia have been reported rarely. Administration of the drug should be discontinued if granulocytopenia occurs.

When rare, serious reactions occur with griseofulvin, they are usually associated with high dosages, long periods of therapy, or both.

Read the entire FDA prescribing information for Grifulvin V (Griseofulvin Microsize)

© Grifulvin V Patient Information is supplied by Cerner Multum, Inc. and Grifulvin V Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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