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Last reviewed on RxList: 10/18/2016
Gyne-Lotrimin Side Effects Center

Last reviewed on RxList 10/28/2016

Gyne-Lotrimin (clotrimazole vaginal cream) is an antifungal medication used to treat vaginal candida (yeast) infections. Gyne-Lotrimin is available over-the-counter and in generic versions. Common side effects of Gyne-Lotrimin include:

  • vaginal or urethral burning/itching/pain/irritation,
  • an increased need to urinate, or
  • lower abdominal cramps.

Seek immediate medical attention if you have rare but serious symptoms of a serious allergic reaction to Gyne-Lotrimin including:

  • rash,
  • itching/swelling (especially of the face/tongue/throat),
  • severe dizziness, or
  • trouble breathing.

Fill the applicator with the cream and then insert one applicatorful dose of Gyne-Lotrimin cream into the vagina every day, preferably at bedtime. Dispose of applicator after use. Repeat this procedure with a new applicator for 7 consecutive days. In order to kill the yeast completely, you must use Gyne-Lotrimin the full seven days, even if symptoms are relieved sooner. Gyne-Lotrimin may interact with other vaginal creams or douches used at the same time. Tell your doctor all medications and supplements you use. Do not use Gyne-Lotrimin for self-treatment if you are pregnant. During pregnancy, Gyne-Lotrimin should be used only when recommended by your doctor. If you are pregnant, follow your doctor's instructions on how to use the applicator to insert this medication. It is unknown whether this drug passes into breast milk. Consult your doctor before breastfeeding.

Our Gyne-Lotrimin (clotrimazole vaginal cream) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Gyne-Lotrimin Consumer Information

Stop using clotrimazole vaginal and seek emergency medical attention if you experience an allergic reaction (shortness of breath; closing of your throat; swelling of your lips, face, or tongue; or hives).

Other, less serious side effects may be more likely to occur. These include burning, itching, irritation of the skin, and an increased need to urinate.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Gyne-Lotrimin (Clotrimazole Vaginal Cream)

Gyne-Lotrimin Professional Information


No information provided.

Read the entire FDA prescribing information for Gyne-Lotrimin (Clotrimazole Vaginal Cream)

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© Gyne-Lotrimin Patient Information is supplied by Cerner Multum, Inc. and Gyne-Lotrimin Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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