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What conditions cause a hematoma?

Conditions that cause a hematoma include:

  • Aneurysm
  • Medications: Blood thinners or anticoagulation medications, including warfarin (Coumadin), aspirin, clopidogrel (Plavix), prasugrel (Effient), rivaroxaban (Xarelto), and apixaban (Eliquis) may increase the potential for spontaneous bleeding and for hematomas to expand because the body cannot efficiently repair blood vessels. This allows blood to continually leak through the damaged areas.
  • Diseases or conditions that may decrease the number of platelets in the bloodstream (thrombocytopenia) or diminish their function: Viral infections (rubella, parvovirus, mumps, chickenpox, HIV, and hepatitis C), aplastic anemia, cancers from other organs, long-term alcohol abuse, and vitamin D deficiency may be associated with hematomas.
  • Orthopedic injuries: Fractures are always associated with hematomas at the fracture site. Fractures of long bones such as the thigh (femur) and upper arm (humerus) can be associated with a significant amount of bleeding.
Reviewed on 9/28/2017

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