House Dust Mite Side Effects Center

Last updated on RxList: 3/15/2022
House Dust Mite Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

What Is House Dust Mite?

House Dust Mite (Dermatophagoides pteronyssinus injection) is indicated for use in the diagnosis of patients with a history of allergy to mites or house dust and for the treatment of patients with a history of mite allergy who have established sensitivity to mites by diagnostic skin testing.

What Are Side Effects of House Dust Mite?

Common side effects of House Dust Mite include:

Dosage for House Dust Mite

The skin test concentration of 10,000 AU/mL of House Dust Mite in dropper vials is used for scratch or prick-puncture testing.

What Drugs, Substances, or Supplements Interact with House Dust Mite?

House Dust Mite may interact with antihistamines, hydroxyzine, and beta-blockers. Tell your doctor all medications and supplements you use.

House Dust Mite During Pregnancy or Breastfeeding

Tell your doctor if you are pregnant or plan to become pregnant before using House Dust Mite; it is unknown how it would affect a fetus. It is unknown if House Dust Mite passes into breast milk. Consult your doctor before breastfeeding.

Additional Information

Our House Dust Mite (Dermatophagoides pteronyssinus injection) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

SLIDESHOW

Could I Be Allergic? Discover Your Allergy Triggers See Slideshow
House Dust Mite Professional Information

SIDE EFFECTS

Adverse systemic reactions usually occur within minutes and consist primarily of allergic symptoms such as generalized skin erythema, urticaria, pruritus, angioedema, rhinitis, wheezing, laryngeal edema and hypotension. Less commonly, nausea, emesis, abdominal cramps, diarrhea and uterine contractions may occur. Severe reactions may cause shock and loss of consciousness. Fatalities have occurred rarely11 . Systemic reactions occur with varying frequency in different clinics. To some extent, the reaction rate is related to the type and dose of administered extract and to the degree of sensitivity of the patient. Despite all precautions, occasional reactions are unavoidable. Reports from regulatory authorities in Sweden to the Center for Biologics Evaluation and Research (CBER) indicated that several deaths have been associated with the use of mite extracts. CBER was subsequently informed that these deaths may have been related to use by physicians or other health professionals untrained in the administration of potent allergens, rather than a product defect. It should be noted that anaphylaxis and deaths following the injection of mite and other extracts also have been reported by the British Committee on Safety in Medicine in the British Medical Journal, 293: 943, 1986.

Local reactions consisting of erythema, itching, swelling, tenderness and sometimes pain may occur at the injection site. These reactions may appear within a few minutes to hours and persist for several days. Local cold applications and oral antihistamines may be effective treatment. For marked and prolonged local reactions, steroids may be helpful.

The treatment of systemic allergic reactions is somewhat dependent upon the symptom complex. Epinephrine hydrochloride 1:1,000 aqueous, in an adult dose of 0.3 - 0.5 mL (or 0.01 mL per kg. for children) administered subcutaneously in the opposite arm is the immediate treatment of choice. A tourniquet should be placed above the site of the extract injection if the injection was done on the extremities. Antihistamines may offer relief of recurrent urticaria, associated skin reactions and gastrointestinal symptoms. Persistent wheezing may necessitate intravenous aminophylline treatment. For profound shock and hypotension, intravenous fluids, vasopressors and oxygen also may be needed.

Maintenance of an open airway is critical if upper airway obstruction is present. Corticosteroids may provide benefit if symptoms are prolonged or recurrent.

Read the entire FDA prescribing information for House Dust Mite (Dermatophagoides Pteronyssinus)

QUESTION

Allergies can best be described as: See Answer

© House Dust Mite Patient Information is supplied by Cerner Multum, Inc. and House Dust Mite Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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