How Do Alpha-2 Adrenergic Agonists Work?

Reviewed on 7/13/2021

HOW DO ALPHA-2 ADRENERGIC AGONISTS WORK?

Alpha-2 adrenergic agonists are drugs used to treat attention deficit hyperactivity disorder (ADHD), high blood pressure, and muscle spasticity associated with multiple sclerosis and spinal cord injury. Alpha-2 adrenergic agonists stimulate alpha-2 adrenergic receptors in the central nervous system and decrease sympathetic nervous system activity. Alpha-2 receptors are found on cells in the sympathetic nervous system. The sympathetic nervous system is the part of the nervous system that produces fight-or-flight response and increases heart rate, blood pressure, breathing rate, and pupil size.

HOW ARE ALPHA-2 ADRENERGIC AGONISTS USED?

Alpha-2 adrenergic agonists are used to treat:

  • ADHD
  • Muscle spasticity
  • Cramps and tightening of the muscles
  • Hypertension (high blood pressure)

WHAT ARE SIDE EFFECTS OF ALPHA-2 ADRENERGIC AGONISTS?

Side effects of alpha-2 adrenergic agonists include:

The information contained herein is not intended to cover all possible side effects, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Check with your doctor or pharmacist to make sure these drugs do not cause any harm when you take them along with other medicines. Never stop taking your medication and never change your dose or frequency without consulting your doctor.

WHAT ARE NAMES OF ALPHA-2 ADRENERGIC AGONISTS?

Generic and brand names of alpha-2 adrenergic agonists include:

QUESTION

Who is at greater risk for developing ADHD? See Answer
References
https://reference.medscape.com/drugs/alpha2-adrenergic-agonists

https://pubchem.ncbi.nlm.nih.gov/compound/Guanfacine#section=Chemical-Vendors

https://pubchem.ncbi.nlm.nih.gov/compound/Tizanidine#section=Substances-by-Category

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