How Do Amide Local Anesthetics Work?

Reviewed on 7/27/2021

HOW DO AMIDE LOCAL ANESTHETICS WORK?

Amide local anesthetics are commonly used for pain control during minor surgery.

Local anesthesia causes a temporary loss of sensation, including pain, without depressing the consciousness. It acts within nerve fibers to inhibit the rapid inflow of sodium necessary for impulse generation. When there is no impulse generation, there is no transmission of pain around that area. Also, there is a loss of sensation around that area.

Amide local anesthetics have an amide link in their structure and are processed in the liver.

WHAT ARE SIDE EFFECTS OF AMIDE LOCAL ANESTHETICS?

Amide local anesthetics can cause the following side effects:

The information contained herein is not intended to cover all possible side effects, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Check with your doctor or pharmacist to make sure these drugs do not cause any harm when you take them along with other medicines. Never stop taking your medication and never change your dose or frequency without consulting your doctor.

HOW ARE AMIDE LOCAL ANESTHETICS USED?

Amide local anesthetics are used for preventing or reducing pain from:

  • Minor surgery
  • Incisions
  • Biopsies
  • Dental procedures
  • Obstetrical procedures

WHAT ARE NAMES OF AMIDE LOCAL ANESTHETICS?

Generic and brand names of amide local anesthetics include:

SLIDESHOW

Back Pain: 16 Back Pain Truths and Myths See Slideshow
References
https://reference.medscape.com/drugs/local-anesthetics-amides

https://www.ncbi.nlm.nih.gov/books/NBK547905/

Health Solutions From Our Sponsors