How Do Anilidopiperidine Opioids Work?

Reviewed on 9/22/2021

How do anilidopiperidine opioids work?

Anilidopiperidine opioids are powerful synthetic opioid medications with rapid onset and short duration of action. Anilidopiperidine opioids are used for sedation during surgical procedures and pain relief (analgesia) from intense breakthrough pain. Anilidopiperidine opioids inhibit pain pathways in the central nervous system, increase pain tolerance and reduce pain perception.

Anilidopiperidine opioids are opioid agonists which work by stimulating a type of opioid receptors known as mu-opioid receptors. Opioid receptors are protein molecules on nerve cell (neuron) membranes in the central and peripheral nervous systems.

Opioid receptors mediate the body’s response to most hormones and some of their functions include modulating pain, stress response, respiration, digestion, mood, and emotion. Stimulation of mu-opioid receptors blocks the release of chemicals (neurotransmitters) that transmit pain signals, resulting in rapid analgesia and sedation.

How are anilidopiperidine opioids used?

Anilidopiperidine opioids are administered as intravenous injections or transmucosal medications which are available as:

  • Sublingual sprays that are sprayed under the tongue
  • Lozenges or tablets that are placed inside the cheek to dissolve

Anilidopiperidine opioids are typically used in the following situations:

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What are side effects of anilidopiperidine opioids?

Side effects of anilidopiperidine opioids may include the following:

Information contained herein is not intended to cover all possible side effects, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Check with your doctor or pharmacist to make sure these drugs do not cause any harm when you take them along with other medicines. Never stop taking your medication and never change your dose or frequency without consulting your doctor.

What are names of some anilidopiperidine opioid drugs?

Generic and brand names of some anilidopiperidine opioid drugs include:

QUESTION

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References
https://reference.medscape.com/drugs/opioids-anilidopiperidine

https://www.ncbi.nlm.nih.gov/books/NBK470456/

https://www.ncbi.nlm.nih.gov/books/NBK554511/

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