How Do Hydrochloric Acid Binders Work?

Reviewed on 5/18/2021

WHAT ARE HYDROCHLORIC ACID BINDERS AND HOW DO THEY WORK?

Hydrochloric acid binders are a class of drugs used to treat metabolic acidosis. Metabolic acidosis is a complication of chronic kidney disease (CKD) and leads to its worsening. Metabolic acidosis develops when the body contains too much acid as the kidneys fail to remove enough acid from the body. Hydrochloric acid binders bind to the hydrochloric acid present in the gastrointestinal tract, resulting in an increase in carbonate ions in the blood. As a result, the excess acid in the body is neutralized for correcting metabolic acidosis.

HOW ARE HYDROCHLORIC ACID BINDERS USED?

Hydrochloric acid binders are administered orally as a suspension. They are designed to treat:

  • Metabolic acidosis in patients with CKD

WHAT ARE SIDE EFFECTS OF HYDROCHLORIC ACID BINDERS?

WHAT ARE DRUG NAMES OF HYDROCHLORIC ACID BINDERS?

There is a single drug Veverimer under hydrochloric acid binders for which the US Food and Drug Administration (FDA) approval is pending.

SLIDESHOW

Kidney Stones: Symptoms, Causes, and Treatment See Slideshow
References
https://reference.medscape.com/drug/veverimer-4000039#91

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