How Do Natriuretic Peptides Work?

Reviewed on 11/19/2021

HOW DO NATRIURETIC PEPTIDES WORK?

Natriuretic peptides are drugs used for treating heart failure.

The heart produces different types of natriuretic peptides found in low levels in the bloodstream. High levels of natriuretic peptides may indicate that the heart is not functioning efficiently.

The recombinant natriuretic peptides bind to natriuretic receptors present in the heart to release guanosine 3'5'-cyclic monophosphate for:

  • Relaxation of heart muscles
  • Dilation of arteries and veins

Thus, the overload on the heart is reduced, improving its overall functioning.

HOW ARE NATRIURETIC PEPTIDES USED?

Natriuretic peptides are used for treating acute heart failure accompanied by shortness of breath.

WHAT ARE SIDE EFFECTS OF NATRIURETIC PEPTIDES?

Natriuretic peptides can cause the following side effects:

The information contained herein is not intended to cover all possible side effects, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Check with your doctor or pharmacist to make sure these drugs do not cause any harm when you take them along with other medicines. Never stop taking your medication and never change your dose or frequency without consulting your doctor.

WHAT ARE NAMES OF NATRIURETIC PEPTIDES?

Generic and brand names of natriuretic peptides include:

SLIDESHOW

Heart Disease: Symptoms, Signs, and Causes See Slideshow
References
https://reference.medscape.com/drugs/natriuretic-peptides

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