What are ophthalmic macrolides and how do they work?
Ophthalmic macrolides are a class of antibiotic medications used to treat bacterial infections in the eyes. Ophthalmic macrolides stop protein synthesis in the bacterial cells and prevent their growth. Ophthalmic macrolides are broad-spectrum antibiotics.
Ophthalmic macrolides are effective against most common gram-positive bacteria, and a few gram-negative bacteria. Bacteria are broadly classified as gram-positive or gram-negative, based on whether they get stained by a dye used in a laboratory test known as the Gram stain test.
Ophthalmic macrolides are active against most gram-positive bacteria such as:
Ophthalmic macrolides are also effective against gram-negative bacteria such as:
How are ophthalmic macrolides used?
Ophthalmic macrolides are solutions or ointments topically applied to the eyes. Ophthalmic macrolides are effective alternative drugs for people with penicillin allergy. They are used to treat the following eye conditions:
What are side effects of ophthalmic macrolides?
Side effects of ophthalmic macrolides may include:
Ocular side effects:
- Dry eye
- Hypersensitivity reactions
- Corneal erosion
- Punctate keratitis (inflammation of the cornea in a pinpoint pattern)
Systemic side effects:
- Contact dermatitis
- Hives (urticaria)
- Taste distortion (dysgeusia)
- Nasal congestion
Eye Health Resources