How Do Ophthalmic Macrolides Work?

What are ophthalmic macrolides and how do they work?

Ophthalmic macrolides are a class of antibiotic medications used to treat bacterial infections in the eyes. Ophthalmic macrolides stop protein synthesis in the bacterial cells and prevent their growth. Ophthalmic macrolides are broad-spectrum antibiotics.

Ophthalmic macrolides are effective against most common gram-positive bacteria, and a few gram-negative bacteria. Bacteria are broadly classified as gram-positive or gram-negative, based on whether they get stained by a dye used in a laboratory test known as the Gram stain test.

Ophthalmic macrolides are active against most gram-positive bacteria such as:

Ophthalmic macrolides are also effective against gram-negative bacteria such as:

How are ophthalmic macrolides used?

Ophthalmic macrolides are solutions or ointments topically applied to the eyes. Ophthalmic macrolides are effective alternative drugs for people with penicillin allergy. They are used to treat the following eye conditions:

  • Bacterial conjunctivitis: Inflammation of the conjunctiva, the clear membrane over the whites of the eye and inner surface of the eyelids, caused by bacterial infection
  • Trachoma: A contagious infection in the eyelid’s inner surface, caused by Chlamydia trachomatis

What are side effects of ophthalmic macrolides?

Side effects of ophthalmic macrolides may include:

Ocular side effects:

Systemic side effects:

Information contained herein is not intended to cover all possible side effects, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Check with your doctor or pharmacist to make sure these drugs do not cause any harm when you take them along with other medicines. Never stop taking your medication and never change your dose or frequency without consulting your doctor.

What are names of some ophthalmic macrolides drugs?

Generic and brand names of some ophthalmic macrolide drugs include:


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