How Do Phosphodiesterase-3 Enzyme Inhibitors Work?

Reviewed on 11/19/2021

HOW DO PHOSPHODIESTERASE-3 ENZYME INHIBITORS WORK?

Phosphodiesterase-3 enzyme (PDE-3) inhibitors are used for the short-term treatment of life-threatening heart failure.

PDE-3 inhibitors treat heart failure by:

  • Increasing the ability of the heart to beat
  • Relaxing the muscles in the blood vessels
  • Slightly increasing the heart rate
  • Dilating the arteries and veins

HOW ARE PHOSPHODIESTERASE-3 ENZYME INHIBITORS USED?

PDE-3 inhibitors are used for treating acute congestive heart failure.

WHAT ARE SIDE EFFECTS OF PHOSPHODIESTERASE-3 ENZYME INHIBITORS?

PDE-3 inhibitors can cause the following side effects:

The information contained herein is not intended to cover all possible side effects, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Check with your doctor or pharmacist to make sure these drugs do not cause any harm when you take them along with other medicines. Never stop taking your medication and never change your dose or frequency without consulting your doctor.

WHAT ARE NAMES OF PHOSPHODIESTERASE-3 ENZYME INHIBITORS?

Generic and brand names of PDE-3 inhibitors include:

  • Milrinone
  • Udenafil (pending FDA approval)

SLIDESHOW

Heart Disease: Symptoms, Signs, and Causes See Slideshow
References
https://reference.medscape.com/drugs/phosphodiesterase-enzyme-inhibitors

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