HOW DO SELECTIVE 5-HT3 RECEPTOR ANTAGONISTS WORK?
- Passage of food from the mouth to the anus (gut motility)
- Intestinal secretions
- Local stimulation of smooth muscle in the intestine to cause contractions
Selective 5-HT3 receptor antagonists prevent the binding of serotonin to 5-HT3 receptors in the intestine and help to:
- Slow gut motility
- Delay the passage of food through the colon and small intestine
- Control bowel urgency
- Improve bowel function
- Relieve cramps associated with diarrhea
Thus, 5-HT3 receptor antagonist drugs are useful to treat diarrhea-predominant IBS.
HOW ARE SELECTIVE 5-HT3 RECEPTOR ANTAGONISTS USED?
WHAT ARE SIDE EFFECTS OF SELECTIVE 5-HT3 RECEPTOR ANTAGONISTS?
Selective 5-HT3 receptor antagonists, when taken orally, can cause some of these side effects:
The information contained herein is not intended to cover all possible side effects, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Check with your doctor or pharmacist to make sure these drugs do not cause any harm when you take them along with other medicines. Never stop taking your medication and never change your dose or frequency without consulting your doctor.