How Does Acetylcysteine Work?

Reviewed on 12/29/2021

How does acetylcysteine work?

Acetylcysteine, also known as N-acetylcysteine, is a mucolytic agent which breaks up the mucus in the respiratory tract and reduces its viscosity, making it easier to cough up and clear from the lungs. Acetylcysteine also has anti-inflammatory and antioxidant properties.

Acetylcysteine lowers mucus viscosity by splitting the disulfide bonds of mucoproteins, which are vital for their structure and stability. Acetylcysteine is also an antioxidant that protects the lungs by scavenging the free radicals generated by inflammatory cells.

How is acetylcyesteine used?

Acetylcysteine is an orally inhaled solution that is turned into a fine mist using a nebulizer. Acetylcysteine is used in the treatment of the following conditions:

FDA-approved:

Off-label:

Orphan designation:

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What are side effects of acetylcysteine?

Side effects of acetylcysteine may include the following:

Information contained herein is not intended to cover all possible side effects, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Check with your doctor or pharmacist to make sure these drugs do not cause any harm when you take them along with other medicines. Never stop taking your medication and never change your dose or frequency without consulting your doctor.

What are names of some acetylcysteine drugs?

Generic and brand names of acetylcysteine drugs include:

  • acetylcysteine
  • N-acetylcysteine
References
https://reference.medscape.com/drug/n-acetylcysteine-mucomyst-acetylcysteine-343425

https://www.ncbi.nlm.nih.gov/books/NBK537183/

https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/mucoprotein

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