How Does Ophthalmic Mitomycin Work?

Reviewed on 6/25/2021

What is ophthalmic mitomycin and how does it work?

Ophthalmic mitomycin is a medication used to prevent scar tissue formation after certain eye surgeries. Mitomycin is a type of antitumor antibiotic that is typically used to stop the growth of cancer cells in certain types of cancers. Mitomycin stops cell growth and division by inhibiting DNA synthesis.

After an eye surgery, the wound healing process normally involves the growth of cells that form new tissue to close the wound. Ophthalmic mitomycin prevents the formation of new tissue which can close openings created in parts of the eye for fluid drainage or other reasons.

How is ophthalmic mitomycin used?

Ophthalmic mitomycin is a solution that is topically applied on the surgical site after the surgery. The surgical site is thoroughly irrigated after two minutes, because the medication can cause cell death if it gets into healthy eye tissue.

The uses of ophthalmic mitomycin include:

What are the side effects of ophthalmic mitomycin?

Side effects of ophthalmic mitomycin may include:

Information contained herein is not intended to cover all possible side effects, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Check with your doctor or pharmacist to make sure these drugs do not cause any harm when you take them along with other medicines. Never stop taking your medication and never change your dose or frequency without consulting your doctor.

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What are names of some ophthalmic mitomycin drugs?

Generic and brand names of ophthalmic mitomycin include:

References
https://reference.medscape.com/drug/mitosol-mitomycin-ophthalmic-999721

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