Are Humira and Hadlima the Same Thing?
Humira (adalimumab) and Hadlima (adalimumab-bwwd) are tumor necrosis factor (TNF) blockers indicated for treatment of rheumatoid arthritis (RA), juvenile idiopathic arthritis (JIA), psoriatic arthritis (PsA), ankylosing spondylitis (AS), adult Crohn's disease (CD), ulcerative colitis (UC), and plaque psoriasis (Ps).
Hadlima is biosimilar to Humira (adalimumab).
Both Humira and Hadlima may interact with abatacept, anakinra, and live vaccines.
What Are Possible Side Effects of Humira?
Side effects of Humira include:
- injection site reactions (redness, itching, pain, bruising, swelling, or bleeding),
- suffy nose,
- sinus pain, or
- stomach pain.
Tell your doctor if you have serious side effects of Humira including:
- fast/irregular/pounding heartbeat,
- stomach pain,
- blood in the stools,
- mental/mood changes,
- severe headache,
- easy bruising or bleeding,
- dark urine,
- yellowing eyes and skin,
- leg pain or swelling,
- numbness or tingling of the arms/hands/legs/feet,
- unexplained muscle weakness,
- difficulty with speaking/chewing/swallowing/facial movements,
- vision changes,
- extreme fatigue,
- joint pain, or
- butterfly-shaped rash on the nose and cheeks.
What Are Possible Side Effects of Hadlima?
Common side effects of Hadlima include:
- infections (e.g. upper respiratory tract, sinusitis),
- injection site reactions (redness, itching, bleeding, pain, and swelling),
- headache, and
What Is Humira?
Humira (adalimumab) is an injectable protein (antibody) used to treat rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, and plaque psoriasis. Humira is also used to treat Crohn's disease after other drugs have been tried without successful treatment of symptoms.
What Is Hadlima?
Hadlima (adalimumab-bwwd) is a tumor necrosis factor (TNF) blocker indicated for treatment of rheumatoid Arthritis (RA), juvenile idiopathic arthritis (JIA), psoriatic arthritis (PsA), ankylosing spondylitis (AS), adult Crohn's disease (CD), ulcerative colitis (UC), and plaque psoriasis (Ps). Hadlima is biosimilar to Humira (adalimumab).
What Drugs Interact With Humira?
Humira may interact with azathioprine or mercaptopurine. Asacol may also interact with pentamidine, tacrolimus, amphotericin B, antibiotics, antiviral medicines, cancer medicine, or aspirin or other NSAIDs (nonsteroidal anti-inflammatory drugs).
Humira may also interact with abatacept, anakinra, infliximab, etanercept, certolizumab pegol, golimumab, or rituximab.
What Drugs Interact With Hadlima?
Hadlima may interact with abatacept, anakinra, warfarin, cyclosporine, theophylline, and live vaccines.
How Should Humira Be Taken?
Humira is given by an injection under the skin. Your doctor will tell you how often to take an injection of Humira. This is based on your condition to be treated. Do not inject Humira more often than you were prescribed.
Do not try to inject Humira yourself until you have been shown the right way to give the injections. If your doctor decides that you or a caregiver may be able to give your injections of Humira at home, you should receive training on the right way to prepare and inject Humira.
Do not miss any doses of Humira unless your doctor says it is okay. If you forget to take Humira, inject a dose as soon as you remember. Then, take your next dose at your regular scheduled time. This will put you back on schedule.
In case you are not sure when to inject Humira, call your doctor or pharmacist.
If you take more Humira than you were told to take, call your doctor.
How Should Hadlima Be Taken?
The dose of Humira to treat adult rheumatoid arthritis and psoriatic arthritis is 50 mg once weekly with or without methotrexate (MTX). The dose of Humira to treat ankylosing spondylitis is 50 mg once weekly. The dose of Humira to treat adult plaque psoriasis is 50 mg twice weekly for 3 months, followed by 50 mg once weekly. The dose of Humira to treat pediatric plaque psoriasis or plaque psoriasis (patients who weigh 63 kg or more) is 50 mg once weekly.
Rheumatoid Arthritis Resources
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Abbvie. Humira Product Monograph.
FDA. Hadlima Product Information.