Humulin R vs. Novolin R

Reviewed on 1/28/2021

Are Humulin R and Novolin R the Same Thing?

Humulin R (insulin [human recombinant]) and Novolin R (insulin glargine [rdna origin]) Injection are forms of insulin indicated as adjuncts to diet and exercise to improve glycemic control in adults and children with type 1 and type 2 diabetes mellitus. Humulin R is a short-acting form of insulin and Novolin R is a long-acting form of insulin.

Side effects of Humulin R and Novolin R that are similar include low blood sugar (hypoglycemia) (symptoms include headache, hunger, weakness, sweating, tremors, irritability, trouble concentrating, rapid breathing, fast heartbeat, fainting, and seizures [severe hypoglycemia can be fatal]) and injection site reactions (e.g., pain, redness, irritation).

Both Humulin R and Novolin R may interact with albuterol, clonidine, reserpine, and beta-blockers.

Humulin R may also interact with guanethidine.

What Are Possible Side Effects of Humulin R?

Common side effects of Humulin R include:

  • injection site reactions (e.g., pain, redness, irritation).

Low blood sugar (hypoglycemia) is the most common side effect of Humulin R.

Symptoms of low blood sugar include:

  • headache,
  • hunger,
  • weakness,
  • sweating,
  • tremors,
  • irritability,
  • trouble concentrating,
  • rapid breathing,
  • fast heartbeat,
  • fainting, or
  • seizure (severe hypoglycemia can be fatal).

Tell your doctor if you have serious side effects of Humulin R including:

What Are Possible Side Effects of Novolin R?

The most common side effect of Novolin R is:

Symptoms of low blood sugar include headache, hunger, weakness, sweating, tremors, irritability, trouble concentrating, rapid breathing, fast heartbeat, fainting, or seizure. Other side effects of Novolin R include:

QUESTION

Diabetes is defined best as... See Answer

What Is Humulin R?

Humulin R (insulin (human recombinant)) is a hormone that is produced in the body used to treat diabetes.

What Is Novolin R?

Novolin R (regular, human insulin [rDNA origin]) is a form of insulin, a naturally occurring hormone, used to control blood sugar in patients with diabetes mellitus. Novolin R is available over-the-counter.

What Drugs Interact With Humulin R?

Humulin R may interact with albuterol, clonidine, reserpine, guanethidine, or beta-blockers. Tell your doctor all medications you are taking.

What Drugs Interact With Novolin R?

Novolin R may interact with oral hypoglycemic agents (OHA), octreotide, monoamine oxidase inhibitors (MAOIs), beta-blockers, ACE inhibitors, salicylates, alcohol, antibiotics, steroids, quinine, quinidine, alpha-blockers, oral contraceptives, thiazides, glucocorticoids, thryroid hormones and sympathomimetics, growth hormone, diazoxide, asparaginase, and nicotinic acid. Tell your doctor all medications and supplements you use.

How Should Humulin R be Taken?

The recommended starting dose of Humulin R for patients 6 years and older is 25 mg once daily in the morning. The dosage of Humulin R may be increased in increments of 10 to 15 mg at intervals of at least 5 days.

How Should Novolin R be Taken?

The dosing of Novolin R is individualized. It is usually given three or more times daily before meals.

SLIDESHOW

Diabetes: What Raises and Lowers Your Blood Sugar Level? See Slideshow
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References
Lilly. Humulin R Product Information.

https://www.humulin.com/insulin-options

Novo Nordisk Medical. Novolin R Product Information.

https://www.novo-pi.com/novolinr.pdf

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