Hycodan

Medical Editor: John P. Cunha, DO, FACOEP Last updated on RxList: 10/29/2021
Hycodan Side Effects Center

What Is Hycodan?

Hycodan (hydrocodone bitartrate and homatropine methylbromide) is a combination of a narcotic cough medicine and a medicine that works against the narcotic to prevent an overdose used to treat cough.

What Are Side Effects of Hycodan?

Common side effects of Hycodan include:

  • nausea due to the use of hydrocodone, which usually goes away after the first few doses.

Other side effects of Hycodan include:

  • lightheadedness,
  • dizziness,
  • drowsiness,
  • vision changes,
  • trouble concentrating,
  • vomiting,
  • constipation, or
  • skin itching or rash.

Tell your doctor if you have serious side effects of Hycodan including:

Dosage for Hycodan

The dose of Hycodan for adults and children 12 years and older is one tablet or 5 mL (1 tsp) of the oral solution every 4 to 6 hours as needed; do not exceed six tablets or 30 mL (6 tsp) in 24 hours. Consult your doctor for pediatric dosing.

What Drugs, Substances, or Supplements Interact with Hycodan?

Hycodan may interact with other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). Tell your doctor all medications you use.

Hycodan During Pregnancy or Breastfeeding

Additional Information

Hycodan should be used only when prescribed during pregnancy. Using this drug near the expected delivery date is not recommended because it may harm a fetus. Infants born to mothers who have been using this medication may have withdrawal symptoms such as irritability, abnormal/persistent crying, vomiting, or diarrhea. Tell your doctor if you notice symptoms in your newborn. This drug may pass into breast milk and could have undesirable effects on a nursing infant. Consult your doctor before breastfeeding. Withdrawal symptoms may occur if you suddenly stop using this drug.

Our Hycodan (hydrocodone bitartrate and homatropine methylbromide) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

QUESTION

Which illness is known as a viral upper respiratory tract infection? See Answer
Hycodan Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Opioid medicine can slow or stop your breathing, and death may occur. A person caring for you should give naloxone and/or seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.

Stop taking this medicine and call your doctor at once if you have:

  • noisy breathing, sighing, shallow breathing;
  • extreme drowsiness, confusion, feeling weak or limp;
  • a seizure;
  • a light-headed feeling, like you might pass out;
  • severe constipation, stomach pain;
  • little or no urination;
  • adrenal gland problems--nausea, vomiting, loss of appetite, dizziness, worsening tiredness or weakness; or
  • high levels of serotonin in the body--agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, diarrhea.

Serious breathing problems may be more likely in older adults and in those who are debilitated or have wasting syndrome or chronic breathing disorders.

Common side effects may include:

  • drowsiness, dizziness;
  • lack of energy, coordination problems;
  • headache, confusion;
  • dry mouth, nausea, vomiting, constipation;
  • tremors, fast or irregular heart rate; or
  • feeling anxious, restless, nervous, or irritable.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Hycodan (Hydrocodone Bitartrate and Homatropine Methylbromide)

SLIDESHOW

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Hycodan Professional Information

SIDE EFFECTS

Central Nervous System

Sedation, drowsiness, mental clouding, lethargy, impairment of mental and physical performance, anxiety, fear, dysphoria, dizziness, psychic dependence, mood changes.

Gastrointestinal System

Nausea and vomiting may occur; they are more frequent in ambulatory than in recumbent patients. Prolonged administration of HYCODAN may produce constipation.

Genitourinary System

Ureteral spasm, spasm of vesicle sphincters and urinary retention have been reported with opiates.

Respiratory Depression

HYCODAN may produce dose-related respiratory depression by acting directly on brain stem respiratory centers (see OVERDOSE). Use of HYCODAN in children less than 6 years of age has been associated with fatal respiratory depression. Overdose with HYCODAN in children 6 years of age and older, in adolescents, and in adults has been associated with fatal respiratory depression.

Postmarketing events seen in children under 6 years of age include accidental overdose, bronchopneumonia, coma, cyanosis, death, death neonatal, dyspnea, pulmonary edema, respiratory arrest, and respiratory depression.

Postmarketing events seen in patients older than 6 years of age include accidental overdose, cardiorespiratory arrest, death due to drug toxicity, non-accidental overdose, and overdose.

Dermatological

Skin rash, pruritus.

Read the entire FDA prescribing information for Hycodan (Hydrocodone Bitartrate and Homatropine Methylbromide)

© Hycodan Patient Information is supplied by Cerner Multum, Inc. and Hycodan Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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