Ibsrela vs. Bentyl

Are Ibsrela and Bentyl the Same Thing?

Ibsrela (tenapanor) and Bentyl (dicyclomine) are used to treat irritable bowel syndrome.

Ibsrela is specifically used to treat irritable bowel syndrome with constipation (IBS-C) in adults.

Ibsrela and Bentyl belong to different drug classes. Ibsrela is a sodium/hydrogen exchanger 3 (NHE3) inhibitor and Bentyl is an anticholinergic.

Side effects of Ibsrela and Bentyl that are similar include abdominal distension/bloating and dizziness.

Side effects of Ibsrela that are different from Bentyl include diarrhea and gas (flatulence).

Side effects of Bentyl that are different from Ibsrela include dry mouth, blurred vision, dry eyes, confusion, agitation, increased heart rate, constipation, difficulty urinating, headache, nervousness, drowsiness, weakness, lightheadedness, flushing, nausea, vomiting, rash, and stuffy nose.

Ibsrela may interact with other drugs.

Bentyl may interact with antacids, alcohol, other medicines that make you sleepy (cold or allergy medicines, sedatives, narcotics, sleeping pills, muscle relaxers, and medicines for seizures, depression, or anxiety), amantadine, digoxin, metoclopramide, atropine, belladonna, benztropine, dimenhydrinate, methscopolamine, scopolamine, bronchodilators, bladder or urinary medications, heart rhythm medications, irritable bowel medications, monoamine oxidase inhibitors (MAOIs), nitrate medications, phenothiazines, steroids, and ulcer medications.

What Are Possible Side Effects of Ibsrela?

Common side effects of Ibsrela include:

  • diarrhea,
  • abdominal distension,
  • gas (flatulence), and
  • dizziness.

What Are Possible Side Effects of Bentyl?

Common side effects of Bentyl include:

  • dry mouth,
  • blurred vision,
  • dry eyes,
  • confusion,
  • agitation,
  • increased heart rate,
  • constipation,
  • difficulty urinating,
  • headache,
  • nervousness,
  • drowsiness,
  • weakness,
  • dizziness,
  • lightheadedness,
  • flushing,
  • nausea,
  • vomiting,
  • rash,
  • stuffy nose, and
  • abdominal bloating

What Is Ibsrela?

Ibsrela (tenapanor) is a sodium/hydrogen exchanger 3 (NHE3) inhibitor indicated for treatment of irritable bowel syndrome with constipation (IBS-C) in adults.

What Is Bentyl?

Bentyl may interact with amantadine, MAO inhibitors, phenothiazines, or antidepressants.

Bentyl may also interact with other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, or anxiety), digoxin, metoclopramide, atropine, belladonna, benztropine, dimenhydrinate, methscopolamine, scopolamine, bronchodilators, bladder or urinary medications, heart rhythm medications, irritable bowel medications, nitrates, steroids, or ulcer medications.

QUESTION

What is irritable bowel syndrome or IBS? See Answer

What Drugs Interact With Ibsrela?

Ibsrela may interact with other drugs. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant before using Ibsrela; maternal use is not expected to result in fetal exposure to the drug. It is unknown if Ibsrela passes into breast milk. Consult your doctor before breastfeeding.

What Drugs Interact With Bentyl?

There may be other drugs that can affect Bentyl. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

How Should Ibsrela Be Taken?

The recommended dosage of Ibsrela in adults is 50 mg, orally twice daily.

How Should Bentyl Be Taken?

The usual doses of Bentyl range from from 20 - 40 mg given 4 times daily.

SLIDESHOW

Digestive Disorders: Common Misconceptions See Slideshow
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References
FDA. Ibsrela Drug Information.

https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/211801s000lbl.pdf

FDA. Bentyl Product Information.

https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/007409s040,007961s026,008370s031lbl.pdf

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