Ilevro Side Effects Center

Last updated on RxList: 9/14/2022
Ilevro Side Effects Center

What Is Ilevro?

Ilevro (nepafenac) ophthalmic suspension, 0.3% is an ophthalmic nonsteroidal anti-inflammatory drug (ophthalmic NSAID) indicated for the treatment of pain and inflammation associated with cataract surgery.

What Are Side Effects of Ilevro?

Common side effects of Ilevro include:

  • the sensation that a foreign body is in the eye,
  • increased intraocular pressure,
  • a sticky sensation in the eye,
  • eye or eyelid swelling,
  • dry eye,
  • crusting of the eyelids,
  • eye discomfort or pain,
  • itchy eyes,
  • sensitivity to light,
  • tearing.

Seek medical care or call 911 at once if you have the following serious side effects:

  • Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
  • Serious heart symptoms such as fast, irregular, or pounding heartbeats; fluttering in your chest; shortness of breath; and sudden dizziness, lightheartedness, or passing out;
  • Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors.

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

Dosage for Ilevro

Ilevro is administered as drops into the affected eye(s). Ilevro should not be administered while wearing contact lenses. Additionally, if more than one topical ophthalmic medication is being used, the medicines must be administered at least five minutes apart.

What Drugs, Substances, or Supplements Interact with Ilevro?

Ilevro may interact with other drugs. Tell your doctor all medications and supplements you use.

Ilevro During Pregnancy or Breastfeeding

Ilevro should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. The use of Ilevro during late pregnancy should be avoided. It is unknown if Ilevro passes into breast milk. Consult your doctor before breastfeeding.

Additional Information

Our Ilevro (nepafenac) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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Ilevro Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Some side effects are caused by cataract surgery and are not side effects of the medication. Call your doctor at once if you have:

  • severe eye pain or redness;
  • eyelid pain, trouble opening your eyes;
  • vision problems;
  • increased sensitivity to light;
  • watery eyes, crusting or drainage of your eyes;
  • puffy eyelids; or
  • unusual bleeding or bruising, or a wound that will not heal.

Common side effects may include

  • blurred or hazy vision;
  • decreased vision;
  • feeling like something is in your eye;
  • sticky feeling in the eye; or
  • increased pressure inside the eye.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Ilevro (Nepafenac Ophthalmic Suspension)


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Ilevro Professional Information


Because clinical studies are conducted under widely varying conditions, adverse reaction rates observed in the clinical studies of a drug cannot be directly compared to the rates in the clinical studies of another drug and may not reflect the rates observed in practice.

Serious And Otherwise Important Adverse Reactions

The following adverse reactions are discussed in greater detail in other sections of labeling.

Ocular Adverse Reactions

The most frequently reported ocular adverse reactions following cataract surgery were capsular opacity, decreased visual acuity, foreign body sensation, increased intraocular pressure, and sticky sensation. These reactions occurred in approximately 5 to 10% of patients.

Other ocular adverse reactions occurring at an incidence of approximately 1 to 5% included conjunctival edema, corneal edema, dry eye, lid margin crusting, ocular discomfort, ocular hyperemia, ocular pain, ocular pruritus, photophobia, tearing and vitreous detachment. Some of these reactions may be the consequence of the cataract surgical procedure.

Non-Ocular Adverse Reactions

Non-ocular adverse reactions reported at an incidence of 1 to 4% included headache, hypertension, nausea/vomiting, and sinusitis.

Read the entire FDA prescribing information for Ilevro (Nepafenac Ophthalmic Suspension)

© Ilevro Patient Information is supplied by Cerner Multum, Inc. and Ilevro Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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